RT Journal Article SR Electronic T1 The group-specific protein marker: a possible indicator of syphilis, not human immunodeficiency virus infection JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 1013 OP 1015 VO 138 IS 11 A1 D. R. Pollard A1 P. Gill A1 A. Day YR 1988 UL http://www.cmaj.ca/content/138/11/1013.abstract AB We wished to compare the frequency of group-specific (Gc) phenotypes in the general population with that in people with human immunodeficiency virus (HIV) infection to find out whether the Gc protein is a marker for susceptibility to HIV infection. We determined the phenotype frequency in 1083 randomly selected serum samples obtained from the Canadian Influenza Survey Studies and compared it with that in 263 serum samples obtained from the Federal Centre for AIDS and the Syphilis Serology Proficiency Testing Laboratory. No association between Gc phenotype and HIV status was found. However, there was a strong association between the Gc protein 1f/1f phenotype and syphilis.