RT Journal Article
SR Electronic
T1 Treatment of superficial bladder cancer
JF Canadian Medical Association Journal
JO CMAJ
FD Canadian Medical Association
SP 1133
OP 1138
VO 122
IS 10
A1 A. Morales
YR 1980
UL http://www.cmaj.ca/content/122/10/1133.abstract
AB Most patients with bladder cancer initially present with localized, potentially curable tumours. Endoscopic surgery offers the best opportunity to eliminate these early lesions, but the rate of tumour recurrence after adequate resection is high (around 70%). Conventional methods of treatment have a place in the management of early bladder neoplasms, but their success rate is still unsatisfactory and they frequently fail to decrease the risk of recurrence. New drugs and more effective forms of administration have enhanced the use of chemotherapeutic agents. Fundamentally different approaches, such as specific immunotherapy, the use of laser energy and photodynamic therapy, are emerging as valuable approaches in the treatment of superficial bladder cancer and the prevention of recurrence. Randomized trials to assess their value and a concerted multidisciplinary effort with combined treatment give hope for effective control of early bladder cancer.