RT Journal Article
SR Electronic
T1 Abnormalities in pulmonary function after brief exposure to toxic metal fumes
JF Canadian Medical Association Journal
JO CMAJ
FD Canadian Medical Association
SP 586
OP 588
VO 119
IS 6
A1 J. S. Anthony
A1 N. Zamel
A1 A. Aberman
YR 1978
UL http://www.cmaj.ca/content/119/6/586.abstract
AB A 26-year-old welder became ill after exposure to zinc and cadmium fumes at work. His initial clinical course was consistent with that of metal fume fever, but persistence of symptoms and signs beyond the usual duration in this condition led to suspicion of a toxic pulmonary reaction to cadmium. The finding of high percentages of both metals in the urine confirmed this diagnosis. Pulmonary function tests showed restriction of lung volumes, with increased elastic recoil and reduced diffusion, but no evidence of airways obstruction. Chest roentgenograms indicated central pulmonary edema, which cleared in 6 days. Follow-up assessment 2 years later showed incomplete improvement of the restrictive ventilatory defect.