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Research

Association of predicted lean body mass and fat mass with cardiovascular events in patients with type 2 diabetes mellitus

Zhenhua Xing, Liang Tang, Jian Chen, Junyu Pei, Pengfei Chen, Zhenfei Fang, Shenghua Zhou and Xinqun Hu
CMAJ September 23, 2019 191 (38) E1042-E1048; DOI: https://doi.org/10.1503/cmaj.190124
Zhenhua Xing
Departments of Cardiovascular Medicine (Xing, Tang, Pei, Chen, Fang, Zhou, Hu) and Emergency Medicine (Xing), The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; University of South China (Chen), Hengyang, China
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Liang Tang
Departments of Cardiovascular Medicine (Xing, Tang, Pei, Chen, Fang, Zhou, Hu) and Emergency Medicine (Xing), The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; University of South China (Chen), Hengyang, China
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Jian Chen
Departments of Cardiovascular Medicine (Xing, Tang, Pei, Chen, Fang, Zhou, Hu) and Emergency Medicine (Xing), The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; University of South China (Chen), Hengyang, China
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Junyu Pei
Departments of Cardiovascular Medicine (Xing, Tang, Pei, Chen, Fang, Zhou, Hu) and Emergency Medicine (Xing), The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; University of South China (Chen), Hengyang, China
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Pengfei Chen
Departments of Cardiovascular Medicine (Xing, Tang, Pei, Chen, Fang, Zhou, Hu) and Emergency Medicine (Xing), The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; University of South China (Chen), Hengyang, China
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Zhenfei Fang
Departments of Cardiovascular Medicine (Xing, Tang, Pei, Chen, Fang, Zhou, Hu) and Emergency Medicine (Xing), The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; University of South China (Chen), Hengyang, China
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Shenghua Zhou
Departments of Cardiovascular Medicine (Xing, Tang, Pei, Chen, Fang, Zhou, Hu) and Emergency Medicine (Xing), The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; University of South China (Chen), Hengyang, China
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Xinqun Hu
Departments of Cardiovascular Medicine (Xing, Tang, Pei, Chen, Fang, Zhou, Hu) and Emergency Medicine (Xing), The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; University of South China (Chen), Hengyang, China
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Online appendices

  • Appendix 1: Anthropometric prediction equations for lean body mass and fat mass
  • Appendix 10: Sensitivity analysis of fat mass index in relation to MACE by excluding patients with age >75 years
  • Appendix 2: Restricted cubic spline analysis of predicted body mass index or fat mass index for the estimation of the risk of the primary and second endpoints after adjusting for multivariate covariates
  • Appendix 3: Hazard ratio (95% CI) of MACE according to fifths of lean body mass index
  • Appendix 4: Hazard ratio (95% CI) of MACE according to fifths of fat mass index
  • Appendix 5: Hazard ratio (95% CI) of MACE according to thirds of lean body mass index
  • Appendix 6: Hazard ratio (95% CI) of MACE according to thirds of fat mass index
  • Appendix 7: Sensitivity analysis of lean body mass index in relation to MACE by excluding MACE event occurred early in the first two years
  • Appendix 8: Sensitivity analysis of fat mass index in relation to MACE by excluding MACE event occurred early in the first two years
  • Appendix 9: Sensitivity analysis of lean body mass index in relation to MACE by excluding patients with age > 75 years

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