Research
Factors influencing decisions by critical care physicians to withdraw life-sustaining treatments in critically ill adult patients with severe traumatic brain injury
Alexis F. Turgeon, Kristin Dorrance, Patrick Archambault, François Lauzier, François Lamontagne, Ryan Zarychanski, Robert Fowler, Lynne Moore, Jacques Lacroix, Shane English, Amélie Boutin, John Muscedere, Karen E.A. Burns, Donald Griesdale, Lauralyn A. McIntyre, Damon Scales, Francis Bernard, Janet Yamada and Janet E. Squires; for the Canadian Traumatic Brain Injury Research Consortium and the Canadian Critical Care Trials Group
CMAJ June 17, 2019 191 (24) E652-E663; DOI: https://doi.org/10.1503/cmaj.190154
Alexis F. Turgeon
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScKristin Dorrance
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MScPatrick Archambault
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScFrançois Lauzier
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScFrançois Lamontagne
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScRyan Zarychanski
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScRobert Fowler
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScLynne Moore
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
PhDJacques Lacroix
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MDShane English
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScAmélie Boutin
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
PhDJohn Muscedere
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScKaren E.A. Burns
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScDonald Griesdale
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScLauralyn A. McIntyre
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD MScDamon Scales
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MD PhDFrancis Bernard
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
MDJanet Yamada
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
RN PhDJanet E. Squires
CHU de Québec — Université Laval Research Centre (Turgeon, Archambault, Lauzier, Moore, Boutin), Population Health and Optimal Health Practices Research Unit, Trauma — Emergency — Critical Care Medicine, and Division of Critical Care Medicine (Turgeon, Archambault, Lauzier), Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Québec, Que.; Clinical Epidemiology Program (Dorrance, English, McIntyre, Squires), Ottawa Hospital Research Institute, Ottawa, Ont.; Departments of Family and Emergency Medicine (Archambault), and Medicine (Lauzier), Faculty of Medicine, Université Laval, Québec, Que.; Department of Medicine (Lamontagne), Université de Sherbrooke; Centre de recherche du CHU de Sherbrooke (Lamontagne), Sherbrooke, Que.; Department of Internal Medicine (Zarychanski), Sections of Critical Care Medicine, Haematology and Medical Oncology, Faculty of Medicine, University of Manitoba, Winnipeg, Man.; Sunnybrook Research Institute (Fowler, Scales), Sunnybrook Health Sciences Centre, Toronto, Ont.; Department of Social and Preventive Medicine (Moore), Université Laval, Québec, Que.; CHU Ste-Justine Research Centre (Lacroix), CHU Ste-Justine and Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Division of Critical Care (English, McIntyre), Department of Medicine, University of Ottawa, Ottawa, Ont.; Department of Critical Care Medicine (Muscedere) and Kingston Health Sciences Centre, Queen’s University, Kingston, Ont.; Interdepartmental Division of Critical Care Medicine (Burns), University of Toronto; Li Ka Shing Knowledge Institute (Burns), St. Michael’s Hospital, Toronto, Ont.; Division of Critical Care Medicine (Griesdale), Department of Medicine, and Department of Anesthesiology, Pharmacology and Therapeutics (Griesdale), University of British Columbia, Vancouver, BC; Department of Medicine (Bernard), Université de Montréal, Montréal, Que.; Daphne Cockwell School of Nursing (Yamada), Ryerson University, Toronto, Ont.; School of Nursing (Squires), University of Ottawa, Ottawa, Ont.
PhDVisual abstract
Files in this Data Supplement: