RE: CMAJ August 10, 2020 192 (32) E913-E918
References
Siraj Mithoowani, Marissa Laureano, Mark A. Crowther, et al. Investigation and management of erythrocytosis. CMAJ 2020;192:E913-E918.
Swerdlow, SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J (Eds): WHO Classificatio nof Tumours of Haematopoietic and Lymphoid Tissues (Revised 4th edition). IARC: Lyon 2017
Figure 1 indicates that Polycythemia Vera can be diagnosed without a bone marrow biopsy. Per Swerdlow et al., (2017), a bone marrow biopsy showing age-adjusted hypercellularity and panymyelosis is required for a diagonsis of Polycythemia Vera to be made.