Skip to main content

Main menu

  • Home
  • Content
    • Current issue
    • Past issues
    • Early releases
    • Collections
    • Sections
    • Blog
    • Infographics & illustrations
    • Podcasts
    • COVID-19 Articles
    • Obituary notices
  • Authors & Reviewers
    • Overview for authors
    • Submission guidelines
    • Submit a manuscript
    • Forms
    • Editorial process
    • Editorial policies
    • Peer review process
    • Publication fees
    • Reprint requests
    • Open access
    • Patient engagement
  • Members & Subscribers
    • Benefits for CMA Members
    • CPD Credits for Members
    • Subscribe to CMAJ Print
    • Subscription Prices
    • Obituary notices
  • Alerts
    • Email alerts
    • RSS
  • JAMC
    • À propos
    • Numéro en cours
    • Archives
    • Sections
    • Abonnement
    • Alertes
    • Trousse média 2023
    • Avis de décès
  • CMAJ JOURNALS
    • CMAJ Open
    • CJS
    • JAMC
    • JPN

User menu

Search

  • Advanced search
CMAJ
  • CMAJ JOURNALS
    • CMAJ Open
    • CJS
    • JAMC
    • JPN
CMAJ

Advanced Search

  • Home
  • Content
    • Current issue
    • Past issues
    • Early releases
    • Collections
    • Sections
    • Blog
    • Infographics & illustrations
    • Podcasts
    • COVID-19 Articles
    • Obituary notices
  • Authors & Reviewers
    • Overview for authors
    • Submission guidelines
    • Submit a manuscript
    • Forms
    • Editorial process
    • Editorial policies
    • Peer review process
    • Publication fees
    • Reprint requests
    • Open access
    • Patient engagement
  • Members & Subscribers
    • Benefits for CMA Members
    • CPD Credits for Members
    • Subscribe to CMAJ Print
    • Subscription Prices
    • Obituary notices
  • Alerts
    • Email alerts
    • RSS
  • JAMC
    • À propos
    • Numéro en cours
    • Archives
    • Sections
    • Abonnement
    • Alertes
    • Trousse média 2023
    • Avis de décès
  • Visit CMAJ on Facebook
  • Follow CMAJ on Twitter
  • Follow CMAJ on Pinterest
  • Follow CMAJ on Youtube
  • Follow CMAJ on Instagram
Practice
Open Access

Metronidazole-induced neurotoxicity

Danica Quickfall, Nick Daneman, Adam A. Dmytriw and David N. Juurlink
CMAJ October 25, 2021 193 (42) E1630; DOI: https://doi.org/10.1503/cmaj.201671
Danica Quickfall
Department of Medicine (Quickfall, Daneman, Juurlink), Sunnybrook Health Sciences Centre; Departments of Medicine and Paediatrics (Quickfall, Daneman, Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (ICES) (Daneman, Juurlink), Toronto, Ont.; Neuroendovascular Program (Dmytriw), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.; Ontario Poison Centre (Juurlink), Toronto, Ont.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nick Daneman
Department of Medicine (Quickfall, Daneman, Juurlink), Sunnybrook Health Sciences Centre; Departments of Medicine and Paediatrics (Quickfall, Daneman, Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (ICES) (Daneman, Juurlink), Toronto, Ont.; Neuroendovascular Program (Dmytriw), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.; Ontario Poison Centre (Juurlink), Toronto, Ont.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Adam A. Dmytriw
Department of Medicine (Quickfall, Daneman, Juurlink), Sunnybrook Health Sciences Centre; Departments of Medicine and Paediatrics (Quickfall, Daneman, Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (ICES) (Daneman, Juurlink), Toronto, Ont.; Neuroendovascular Program (Dmytriw), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.; Ontario Poison Centre (Juurlink), Toronto, Ont.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David N. Juurlink
Department of Medicine (Quickfall, Daneman, Juurlink), Sunnybrook Health Sciences Centre; Departments of Medicine and Paediatrics (Quickfall, Daneman, Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (ICES) (Daneman, Juurlink), Toronto, Ont.; Neuroendovascular Program (Dmytriw), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.; Ontario Poison Centre (Juurlink), Toronto, Ont.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Responses
  • Metrics
  • PDF
Loading

Article Information

vol. 193 no. 42 E1630
DOI 
https://doi.org/10.1503/cmaj.201671
PubMed 
34697097
History 
  • Published online October 24, 2021.
Copyright & Usage 
© 2021 CMA Joule Inc. or its licensors This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY-NC-ND 4.0) licence, which permits use, distribution and reproduction in any medium, provided that the original publication is properly cited, the use is noncommercial (i.e., research or educational use), and no modifications or adaptations are made. See: https://creativecommons.org/licenses/by-nc-nd/4.0/

Author Information

  1. Danica Quickfall, MD CM,
  2. Nick Daneman, MD,
  3. Adam A. Dmytriw, MD MPH,
  4. David N. Juurlink, MD PhD
  1. Department of Medicine (Quickfall, Daneman, Juurlink), Sunnybrook Health Sciences Centre; Departments of Medicine and Paediatrics (Quickfall, Daneman, Juurlink), University of Toronto; Institute for Clinical Evaluative Sciences (ICES) (Daneman, Juurlink), Toronto, Ont.; Neuroendovascular Program (Dmytriw), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.; Ontario Poison Centre (Juurlink), Toronto, Ont.
  1. Correspondence to: David Juurlink, david.juurlink{at}ices.on.ca

Statistics from Altmetric.com

Usage statistics: October 2021 to March 2023

AbstractFullPdf
Oct 202102588684
Nov 20210830370
Dec 2021027277
Jan 2022021691
Feb 2022017844
Mar 2022017856
Apr 2022024481
May 2022017558
Jun 2022016440
Jul 2022016331
Aug 2022015559
Sep 2022013850
Oct 2022016236
Nov 2022016649
Dec 2022014044
Jan 2023014139
Feb 2023011617
Mar 2023010318
PreviousNext
Back to top

In this issue

Canadian Medical Association Journal: 193 (42)
CMAJ
Vol. 193, Issue 42
25 Oct 2021
  • Table of Contents
  • Index by author

Article tools

Respond to this article
Print
Download PDF
Article Alerts
To sign up for email alerts or to access your current email alerts, enter your email address below:
Email Article

Thank you for your interest in spreading the word on CMAJ.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Metronidazole-induced neurotoxicity
(Your Name) has sent you a message from CMAJ
(Your Name) thought you would like to see the CMAJ web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Metronidazole-induced neurotoxicity
Danica Quickfall, Nick Daneman, Adam A. Dmytriw, David N. Juurlink
CMAJ Oct 2021, 193 (42) E1630; DOI: 10.1503/cmaj.201671

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
‍ Request Permissions
Share
Metronidazole-induced neurotoxicity
Danica Quickfall, Nick Daneman, Adam A. Dmytriw, David N. Juurlink
CMAJ Oct 2021, 193 (42) E1630; DOI: 10.1503/cmaj.201671
Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like

Jump to section

  • Article
    • Metronidazole-induced neurotoxicity is underappreciated
    • Metronidazole-induced neurotoxicity can present with a variety of clinical syndromes
    • Dose and duration of treatment are the primary risk factors, but symptoms may appear early and with small doses
    • Up to 90% of patients with central nervous system involvement have characteristic lesions on magnetic resonance imaging (MRI)
    • Discontinuing metronidazole usually results in improvement
    • Footnotes
    • References
  • Responses
  • Metrics
  • PDF

Related Articles

  • Neurotoxicité du métronidazole
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Screening for primary aldosteronism in primary care
  • Duodenal duplication cyst in a 61-year-old man
  • A young woman with fever and polyserositis caused by familial Mediterranean fever
Show more Practice

Similar Articles

Collections

  • Article Types
    • Five Things to Know About
  • Topics
    • Drugs: adverse reactions
    • Neurology
    • Pharmacology & toxicology

 

View Latest Classified Ads

Content

  • Current issue
  • Past issues
  • Collections
  • Sections
  • Blog
  • Podcasts
  • Alerts
  • RSS
  • Early releases

Information for

  • Advertisers
  • Authors
  • Reviewers
  • CMA Members
  • CPD credits
  • Media
  • Reprint requests
  • Subscribers

About

  • General Information
  • Journal staff
  • Editorial Board
  • Advisory Panels
  • Governance Council
  • Journal Oversight
  • Careers
  • Contact
  • Copyright and Permissions
  • Accessibiity
  • CMA Civility Standards
CMAJ Group

Copyright 2023, CMA Impact Inc. or its licensors. All rights reserved. ISSN 1488-2329 (e) 0820-3946 (p)

All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Canadian Medical Association or its subsidiaries.

To receive any of these resources in an accessible format, please contact us at CMAJ Group, 500-1410 Blair Towers Place, Ottawa ON, K1J 9B9; p: 1-888-855-2555; e: cmajgroup@cmaj.ca

Powered by HighWire