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Recent cannabis use and myocardial infarction in young adults: a cross-sectional study
Karim S. Ladha, Nikhil Mistry, Duminda N. Wijeysundera, Hance Clarke, Subodh Verma, Gregory M.T. Hare and C. David Mazer
CMAJ September 07, 2021 193 (35) E1377-E1384; DOI: https://doi.org/10.1503/cmaj.202392
Karim S. Ladha
Department of Anesthesia (Ladha, Mistry, Wijeysundera, Hare, Mazer), St. Michael’s Hospital, Unity Health Toronto and Institute of Health Policy, Management, and Evaluation (Ladha, Wijeysundera) and Institute of Medical Sciences (Mistry, Mazer) and Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network (Clarke) and Division of Cardiac Surgery (Verma), St. Michael’s Hospital, Unity Health Toronto and Department of Surgery (Verma) and Department of Physiology (Hare, Mazer), University of Toronto, Toronto, Ont.
Nikhil Mistry
Department of Anesthesia (Ladha, Mistry, Wijeysundera, Hare, Mazer), St. Michael’s Hospital, Unity Health Toronto and Institute of Health Policy, Management, and Evaluation (Ladha, Wijeysundera) and Institute of Medical Sciences (Mistry, Mazer) and Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network (Clarke) and Division of Cardiac Surgery (Verma), St. Michael’s Hospital, Unity Health Toronto and Department of Surgery (Verma) and Department of Physiology (Hare, Mazer), University of Toronto, Toronto, Ont.
Duminda N. Wijeysundera
Department of Anesthesia (Ladha, Mistry, Wijeysundera, Hare, Mazer), St. Michael’s Hospital, Unity Health Toronto and Institute of Health Policy, Management, and Evaluation (Ladha, Wijeysundera) and Institute of Medical Sciences (Mistry, Mazer) and Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network (Clarke) and Division of Cardiac Surgery (Verma), St. Michael’s Hospital, Unity Health Toronto and Department of Surgery (Verma) and Department of Physiology (Hare, Mazer), University of Toronto, Toronto, Ont.
Hance Clarke
Department of Anesthesia (Ladha, Mistry, Wijeysundera, Hare, Mazer), St. Michael’s Hospital, Unity Health Toronto and Institute of Health Policy, Management, and Evaluation (Ladha, Wijeysundera) and Institute of Medical Sciences (Mistry, Mazer) and Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network (Clarke) and Division of Cardiac Surgery (Verma), St. Michael’s Hospital, Unity Health Toronto and Department of Surgery (Verma) and Department of Physiology (Hare, Mazer), University of Toronto, Toronto, Ont.
Subodh Verma
Department of Anesthesia (Ladha, Mistry, Wijeysundera, Hare, Mazer), St. Michael’s Hospital, Unity Health Toronto and Institute of Health Policy, Management, and Evaluation (Ladha, Wijeysundera) and Institute of Medical Sciences (Mistry, Mazer) and Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network (Clarke) and Division of Cardiac Surgery (Verma), St. Michael’s Hospital, Unity Health Toronto and Department of Surgery (Verma) and Department of Physiology (Hare, Mazer), University of Toronto, Toronto, Ont.
Gregory M.T. Hare
Department of Anesthesia (Ladha, Mistry, Wijeysundera, Hare, Mazer), St. Michael’s Hospital, Unity Health Toronto and Institute of Health Policy, Management, and Evaluation (Ladha, Wijeysundera) and Institute of Medical Sciences (Mistry, Mazer) and Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network (Clarke) and Division of Cardiac Surgery (Verma), St. Michael’s Hospital, Unity Health Toronto and Department of Surgery (Verma) and Department of Physiology (Hare, Mazer), University of Toronto, Toronto, Ont.
C. David Mazer
Department of Anesthesia (Ladha, Mistry, Wijeysundera, Hare, Mazer), St. Michael’s Hospital, Unity Health Toronto and Institute of Health Policy, Management, and Evaluation (Ladha, Wijeysundera) and Institute of Medical Sciences (Mistry, Mazer) and Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network (Clarke) and Division of Cardiac Surgery (Verma), St. Michael’s Hospital, Unity Health Toronto and Department of Surgery (Verma) and Department of Physiology (Hare, Mazer), University of Toronto, Toronto, Ont.

Data supplements
Online appendices
- Appendix 1: Variables Used for Analysis
- Appendix 2: Confounder Analysis
- Appendix 3: Propensity-Score Matched Analysis
- Appendix 4: Detailed Summary of Missing Data
- Appendix 5: Unweighted and Unadjusted Absolute Risk Differences for Outcomes
- Appendix 6: Full Regression Models for Primary Outcome Analysis
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- Burns, M. M., & Toce, M. S. (2021). Pediatric cannabis use and cardiac complications. CMAJ, 193(45), E1737. Accessed March 29, 2023. https://doi.org/10.1503/cmaj.80288.
- Ladha, K. S., Mistry, N., Wijeysundera, D. N., Clarke, H., Verma, S., Hare, G. M., & Mazer, C. D. (2022). Usage récent de cannabis et infarctus du myocarde chez de jeunes adultes: étude transversale. CMAJ, 194(12), E464-E472. Accessed March 29, 2023. https://doi.org/10.1503/cmaj.202392-f.
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Recent cannabis use and myocardial infarction in young adults: a cross-sectional study
Karim S. Ladha, Nikhil Mistry, Duminda N. Wijeysundera, Hance Clarke, Subodh Verma, Gregory M.T. Hare, C. David Mazer
CMAJ Sep 2021, 193 (35) E1377-E1384; DOI: 10.1503/cmaj.202392
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