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Practice
Open Access

How to use antihistamines

Derek K. Chu, Paul Oykhman and Gordon L. Sussman
CMAJ April 06, 2021 193 (14) E478-E479; DOI: https://doi.org/10.1503/cmaj.201959
Derek K. Chu
Division of Clinical Immunology and Allergy, Department of Medicine (Chu, Oykhman), and Department of Health Research Methods, Evidence & Impact (Chu), McMaster University and The Research Institute of St. Joe’s Hamilton, Ont.; Division of Clinical Immunology & Allergy (Sussman), Department of Medicine, University of Toronto, Toronto, Ont.
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Paul Oykhman
Division of Clinical Immunology and Allergy, Department of Medicine (Chu, Oykhman), and Department of Health Research Methods, Evidence & Impact (Chu), McMaster University and The Research Institute of St. Joe’s Hamilton, Ont.; Division of Clinical Immunology & Allergy (Sussman), Department of Medicine, University of Toronto, Toronto, Ont.
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Gordon L. Sussman
Division of Clinical Immunology and Allergy, Department of Medicine (Chu, Oykhman), and Department of Health Research Methods, Evidence & Impact (Chu), McMaster University and The Research Institute of St. Joe’s Hamilton, Ont.; Division of Clinical Immunology & Allergy (Sussman), Department of Medicine, University of Toronto, Toronto, Ont.
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Article Information

vol. 193 no. 14 E478-E479
DOI 
https://doi.org/10.1503/cmaj.201959
PubMed 
33824145
History 
  • Published online April 5, 2021.
Copyright & Usage 
© 2021 Joule Inc. or its licensors This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY-NC-ND 4.0) licence, which permits use, distribution and reproduction in any medium, provided that the original publication is properly cited, the use is noncommercial (i.e., research or educational use), and no modifications or adaptations are made. See: https://creativecommons.org/licenses/by-nc-nd/4.0/

Author Information

  1. Derek K. Chu, MD PhD,
  2. Paul Oykhman, MD MSc,
  3. Gordon L. Sussman, MD
  1. Division of Clinical Immunology and Allergy, Department of Medicine (Chu, Oykhman), and Department of Health Research Methods, Evidence & Impact (Chu), McMaster University and The Research Institute of St. Joe’s Hamilton, Ont.; Division of Clinical Immunology & Allergy (Sussman), Department of Medicine, University of Toronto, Toronto, Ont.
  1. Correspondence to: Derek Chu, chudk{at}mcmaster.ca

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Canadian Medical Association Journal: 193 (14)
CMAJ
Vol. 193, Issue 14
6 Apr 2021
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How to use antihistamines
Derek K. Chu, Paul Oykhman, Gordon L. Sussman
CMAJ Apr 2021, 193 (14) E478-E479; DOI: 10.1503/cmaj.201959

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How to use antihistamines
Derek K. Chu, Paul Oykhman, Gordon L. Sussman
CMAJ Apr 2021, 193 (14) E478-E479; DOI: 10.1503/cmaj.201959
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  • Article
    • Antihistamines are among the most commonly and incorrectly used medicines worldwide
    • First-generation antihistamines are associated with substantial and sometimes fatal adverse effects
    • Newer antihistamines are safer, as affordable and as efficacious as first-generation antihistamines
    • Antihistamines should not be used instead of epinephrine to treat anaphylaxis
    • Most antihistamines are safe during pregnancy and breastfeeding
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