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Open Access

Fatal respiratory diphtheria in a visitor to Canada

Scott Cholewa, Fareen Karachiwalla, Sarah E. Wilson, Jeya Nadarajah and Julianne V. Kus
CMAJ January 04, 2021 193 (1) E19-E22; DOI: https://doi.org/10.1503/cmaj.200707
Scott Cholewa
Public Health Branch (Cholewa, Karachiwalla), Regional Municipality of York, Newmarket, Ont.; Dalla Lana School of Public Health (Karachiwalla, Wilson), and Faculty of Medicine (Nadarajah), and Department of Laboratory Medicine and Pathobiology (Kus), University of Toronto; Public Health Ontario (Wilson, Kus), Toronto, Ont.; Department of Family Medicine, School of Medicine (Karachiwalla), Queen’s University, Kingston, Ont.; Institute for Clinical Evaluative Studies, (Wilson), Toronto, Ont.
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Fareen Karachiwalla
Public Health Branch (Cholewa, Karachiwalla), Regional Municipality of York, Newmarket, Ont.; Dalla Lana School of Public Health (Karachiwalla, Wilson), and Faculty of Medicine (Nadarajah), and Department of Laboratory Medicine and Pathobiology (Kus), University of Toronto; Public Health Ontario (Wilson, Kus), Toronto, Ont.; Department of Family Medicine, School of Medicine (Karachiwalla), Queen’s University, Kingston, Ont.; Institute for Clinical Evaluative Studies, (Wilson), Toronto, Ont.
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Sarah E. Wilson
Public Health Branch (Cholewa, Karachiwalla), Regional Municipality of York, Newmarket, Ont.; Dalla Lana School of Public Health (Karachiwalla, Wilson), and Faculty of Medicine (Nadarajah), and Department of Laboratory Medicine and Pathobiology (Kus), University of Toronto; Public Health Ontario (Wilson, Kus), Toronto, Ont.; Department of Family Medicine, School of Medicine (Karachiwalla), Queen’s University, Kingston, Ont.; Institute for Clinical Evaluative Studies, (Wilson), Toronto, Ont.
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Jeya Nadarajah
Public Health Branch (Cholewa, Karachiwalla), Regional Municipality of York, Newmarket, Ont.; Dalla Lana School of Public Health (Karachiwalla, Wilson), and Faculty of Medicine (Nadarajah), and Department of Laboratory Medicine and Pathobiology (Kus), University of Toronto; Public Health Ontario (Wilson, Kus), Toronto, Ont.; Department of Family Medicine, School of Medicine (Karachiwalla), Queen’s University, Kingston, Ont.; Institute for Clinical Evaluative Studies, (Wilson), Toronto, Ont.
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Julianne V. Kus
Public Health Branch (Cholewa, Karachiwalla), Regional Municipality of York, Newmarket, Ont.; Dalla Lana School of Public Health (Karachiwalla, Wilson), and Faculty of Medicine (Nadarajah), and Department of Laboratory Medicine and Pathobiology (Kus), University of Toronto; Public Health Ontario (Wilson, Kus), Toronto, Ont.; Department of Family Medicine, School of Medicine (Karachiwalla), Queen’s University, Kingston, Ont.; Institute for Clinical Evaluative Studies, (Wilson), Toronto, Ont.
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  • RE: Respiratory presentations during a Covid-19 pandemic
    Anthony J Walter [BA MB BCH LMCC]
    Posted on: 09 January 2021
  • RE: oropharyngeal examination
    John G. Young [MD,FRCSC]
    Posted on: 04 January 2021
  • Posted on: (9 January 2021)
    RE: Respiratory presentations during a Covid-19 pandemic
    • Anthony J Walter [BA MB BCH LMCC], Retired family physician, Surrey Memorial Hospital, retired

    The January 4th 2021 CMAJ report of a fatal respiratory diphtheria case in a 69 year-old visitor to Canada, is a sobering reminder of unusual diseases that one needs to consider in primary care medicine. The Key Points included with this article are important, but is there one missing?
    A "telemedicine clinic" review advised the patient to present to the Emergency Department immediately; was this the Covid-19 hot-line? If so, the assessing nurse is to be congratulated in recognizing the urgent nature of the patient's symptoms.
    A relative presenting to the 811 phone line with a cough, was told to phone her GP, who in turn recommended that she make an appointment with the local hospital Covid clinic for appraisal and get a naso-pharyngeal swab taken; there, the physician's recommendation was to presume a diagnosis of corona virus and to isolate oneself for 14 days.
    Over the next few months of persistent cough, this sequence was repeated 3 times (in addition to chest imaging and bloodwork). Eventually, resolution of the coughing bouts occurred within a few hours of prescription of a broncho-dilator.
    Like the old adage "all that glitters is not gold", during the pandemic all coughs are not caused by Covid-19, a key point.

    Competing Interests: None declared.

    References

    • Scott Cholewa, Fareen Karachiwalla, Sarah E. Wilson, et al. Fatal respiratory diphtheria in a visitor to Canada. CMAJ 2021;193:E19-E22.
  • Posted on: (4 January 2021)
    RE: oropharyngeal examination
    • John G. Young [MD,FRCSC], retired otolaryngologist, retired adjunct professor, U of O, Department of Otolaryngology

    The complaint of 'something' in the throat hopefully elicited a proper oropharyngeal examination including endoscopy of the upper airway. The physical findings as they are for 'mono' are often quite characteristic. There is no substitute for carefully listening to the patient and a complete physical examination and of course an open and curious mind. J.G. Young, MD FRCS(C) ret'd

    Competing Interests: None declared.

    References

    • Scott Cholewa, Fareen Karachiwalla, Sarah E. Wilson, et al. Fatal respiratory diphtheria in a visitor to Canada. CMAJ 2021;193:E19-E22.
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Canadian Medical Association Journal: 193 (1)
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4 Jan 2021
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Fatal respiratory diphtheria in a visitor to Canada
Scott Cholewa, Fareen Karachiwalla, Sarah E. Wilson, Jeya Nadarajah, Julianne V. Kus
CMAJ Jan 2021, 193 (1) E19-E22; DOI: 10.1503/cmaj.200707

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Fatal respiratory diphtheria in a visitor to Canada
Scott Cholewa, Fareen Karachiwalla, Sarah E. Wilson, Jeya Nadarajah, Julianne V. Kus
CMAJ Jan 2021, 193 (1) E19-E22; DOI: 10.1503/cmaj.200707
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