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Practice: Cases

Prosthetic joint infection after total hip arthroplasty caused by Lactobacillus paracasei

Charlie Tan, James L. Howard and Lise Bondy
CMAJ November 02, 2020 192 (44) E1357-E1360; DOI: https://doi.org/10.1503/cmaj.201106
Charlie Tan
Division of Infectious Diseases (Tan), University of Toronto, Toronto, Ont.; Division of Orthopaedic Surgery (Howard), Western University; Division of Infectious Diseases (Bondy), St. Joseph’s Health Care, London, Ont.
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James L. Howard
Division of Infectious Diseases (Tan), University of Toronto, Toronto, Ont.; Division of Orthopaedic Surgery (Howard), Western University; Division of Infectious Diseases (Bondy), St. Joseph’s Health Care, London, Ont.
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Lise Bondy
Division of Infectious Diseases (Tan), University of Toronto, Toronto, Ont.; Division of Orthopaedic Surgery (Howard), Western University; Division of Infectious Diseases (Bondy), St. Joseph’s Health Care, London, Ont.
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    Figure 1:

    Computed tomography scan of the pelvis showing a complex fluid collection around the right prosthetic hip (red arrow) in an 82-year-old woman who was subsequently diagnosed with a prosthetic joint infection after right total hip arthroplasty caused by Lactobacillus paracasei. The fluid collection extended inferiorly along the femoral shaft and superiorly along the iliopsoas muscle.

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    Box 1: Indications for, and associated antibiotic management of, the most common surgical options for treatment of prosthetic joint infections4
    SurgeryIndicationsAssociated antibiotic management
    Débridement, antibiotics and implant retention
    • Infection within 30 days from implantation

    • Duration of symptoms < 3 weeks

    • Well-fixed prosthesis with no sinus tract

    • Microbiologic etiology identified preoperatively and susceptible to highly bioavailable oral antibiotics

    Up to 6 weeks of intravenous antibiotics, followed by 6 weeks of highly bioavailable oral antibiotics (extended to 12 weeks for infections of knee arthroplasties)
    1-stage revision arthroplasty
    • Total hip arthroplasty

    • No important comorbidities

    • Healthy reserve of bone and soft tissue

    • No sinus tract

    • Microbiologic etiology identified preoperatively and susceptible to highly bioavailable oral antibiotics

    Up to 6 weeks of intravenous antibiotics, followed by 6 weeks of highly bioavailable oral antibiotics (extended to 12 weeks for infections of knee arthroplasties)
    2-stage revision arthroplasty
    • Difficult-to-treat microorganisms (e.g., MRSA, Candida, highly resistant organisms)

    • Poor soft tissue but adequate bone stock

    • Presence of sinus tract is not a contraindication

    • No previous 2-stage revision arthroplasty for infection

    • Patient able to undergo 2 separate surgeries

    • Anticipated good functional outcome

    4–6 weeks of intravenous or highly bioavailable oral antibiotics after first stage
    • Note: MRSA = methicillin-resistant Staphylococcus aureus.

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Canadian Medical Association Journal: 192 (44)
CMAJ
Vol. 192, Issue 44
2 Nov 2020
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Prosthetic joint infection after total hip arthroplasty caused by Lactobacillus paracasei
Charlie Tan, James L. Howard, Lise Bondy
CMAJ Nov 2020, 192 (44) E1357-E1360; DOI: 10.1503/cmaj.201106

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Prosthetic joint infection after total hip arthroplasty caused by Lactobacillus paracasei
Charlie Tan, James L. Howard, Lise Bondy
CMAJ Nov 2020, 192 (44) E1357-E1360; DOI: 10.1503/cmaj.201106
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