Practice
Penicillin allergy
David J. McCullagh and Derek K. Chu
CMAJ February 25, 2019 191 (8) E231; DOI: https://doi.org/10.1503/cmaj.181117
David J. McCullagh
Divisions of Infectious Disease (McCullagh), and Clinical Immunology and Allergy (Chu), Department of Medicine, McMaster University, Hamilton, Ont.
MB BCh BAODerek K. Chu
Divisions of Infectious Disease (McCullagh), and Clinical Immunology and Allergy (Chu), Department of Medicine, McMaster University, Hamilton, Ont.
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Penicillin allergy
David J. McCullagh, Derek K. Chu
CMAJ Feb 2019, 191 (8) E231; DOI: 10.1503/cmaj.181117
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- Penicillin allergy is commonly reported, but 9 out of 10 times, penicillin will be tolerated if administered
- The label of penicillin allergy is bad for patients and the health care system
- Patients reporting penicillin allergy can be easily risk stratified to determine whether they require specialist evaluation
- Penicillin allergy is lost over time, with resolution in 80% of people over 10 years, and in 50% over 5 years
- Allergy referral and testing is vastly underused, but is safe, accurate, rapid and cost-effective
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