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Research

Gestational diabetes associated with incident diabetes in childhood and youth: a retrospective cohort study

Andrea L. Blotsky, Elham Rahme, Mourad Dahhou, Meranda Nakhla and Kaberi Dasgupta
CMAJ April 15, 2019 191 (15) E410-E417; DOI: https://doi.org/10.1503/cmaj.181001
Andrea L. Blotsky
Department of Medicine (Blotsky, Rahme, Dasgupta), McGill University; Centre for Outcomes Research and Evaluation (Blotsky, Rahme, Dahhou, Nakhla, Dasgupta), Research Institute of the McGill University Health Centre; Department of Pediatrics (Nakhla), Division of Endocrinology and Metabolism, McGill University, Montréal, Que.
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Elham Rahme
Department of Medicine (Blotsky, Rahme, Dasgupta), McGill University; Centre for Outcomes Research and Evaluation (Blotsky, Rahme, Dahhou, Nakhla, Dasgupta), Research Institute of the McGill University Health Centre; Department of Pediatrics (Nakhla), Division of Endocrinology and Metabolism, McGill University, Montréal, Que.
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Mourad Dahhou
Department of Medicine (Blotsky, Rahme, Dasgupta), McGill University; Centre for Outcomes Research and Evaluation (Blotsky, Rahme, Dahhou, Nakhla, Dasgupta), Research Institute of the McGill University Health Centre; Department of Pediatrics (Nakhla), Division of Endocrinology and Metabolism, McGill University, Montréal, Que.
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Meranda Nakhla
Department of Medicine (Blotsky, Rahme, Dasgupta), McGill University; Centre for Outcomes Research and Evaluation (Blotsky, Rahme, Dahhou, Nakhla, Dasgupta), Research Institute of the McGill University Health Centre; Department of Pediatrics (Nakhla), Division of Endocrinology and Metabolism, McGill University, Montréal, Que.
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Kaberi Dasgupta
Department of Medicine (Blotsky, Rahme, Dasgupta), McGill University; Centre for Outcomes Research and Evaluation (Blotsky, Rahme, Dahhou, Nakhla, Dasgupta), Research Institute of the McGill University Health Centre; Department of Pediatrics (Nakhla), Division of Endocrinology and Metabolism, McGill University, Montréal, Que.
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    Figure 1:

    Flowchart showing selection of gestational diabetes mellitus (GDM) and non-GDM cohorts. Triads and matched triads were excluded if the father had at least 1 diabetes code during 3 years before delivery, or if the mother had at least 1 diabetes code during 3 years before delivery but not including pregnancy period (estimated by gestational age).

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    Figure 2:

    Kaplan–Meier curve for diabetes-free survival in offspring. (A) Y-axis from 0% to 100%; (B) y-axis from 98.5% to 100% to illustrate the differences between groups. Note: GDM = gestational diabetes mellitus.

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    Table 1:

    Characteristics by status of gestational diabetes mellitus in mother

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    Table 2:

    Hazard ratios for diabetes in children and youth

    Table 2:
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Canadian Medical Association Journal: 191 (15)
CMAJ
Vol. 191, Issue 15
15 Apr 2019
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Gestational diabetes associated with incident diabetes in childhood and youth: a retrospective cohort study
Andrea L. Blotsky, Elham Rahme, Mourad Dahhou, Meranda Nakhla, Kaberi Dasgupta
CMAJ Apr 2019, 191 (15) E410-E417; DOI: 10.1503/cmaj.181001

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Gestational diabetes associated with incident diabetes in childhood and youth: a retrospective cohort study
Andrea L. Blotsky, Elham Rahme, Mourad Dahhou, Meranda Nakhla, Kaberi Dasgupta
CMAJ Apr 2019, 191 (15) E410-E417; DOI: 10.1503/cmaj.181001
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