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- Immunoglobulin E (IgE)–mediated vaccine allergies are uncommon, manifesting within minutes as urticaria, angioedema, wheeze or anaphylaxis
- The most common adverse events of vaccines are fever, local pain or irritation, and local redness or swelling, which are not signs of allergy
- Patients with egg allergy can be safely vaccinated with several vaccines without any special precautions
- Vaccine allergies are typically unpredictable and specific to a single vaccine
- Even if patients are truly allergic to a vaccine, allergists can often safely vaccinate them
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