Age†, yr, median (IQR) | 72 (60–80) | 72 (60–80) | 72 (61–81) | 0.03 |
Sex, female | 12 360 (46.9) | 7127 (44.7) | 5233 (50.2) | 0.11 |
Stroke type |
Stroke | 15 950 (60.5) | 15 950 (100.0) | – | |
TIA | 10 416 (39.5) | – | 10 416 (100.0) | – |
Clinical comorbidity |
Prior stroke | 3715 (14.1) | 2175 (13.6) | 1540 (14.8) | 0.03 |
Prior acute MI | 2030 (7.7) | 1334 (8.4) | 696 (6.7) | 0.06 |
Congestitve heart failure | 3563 (13.5) | 2295 (14.4) | 1268 (12.2) | 0.07 |
Hypertension | 19 521 (74.0) | 12 282 (77.0) | 7239 (69.5) | 0.17 |
Diabetes mellitus | 7741 (29.4) | 5004 (31.4) | 2737 (26.3) | 0.11 |
Hyperlipidemia | 5232 (19.8) | 2964 (18.6) | 2268 (21.8) | 0.08 |
Atrial fibrillation | 4591 (17.4) | 3254 (20.4) | 1337 (12.8) | 0.20 |
Canadian Neurological Scale Group† (19) |
Mild (≥ 8) | 22 364 (86.3) | 12 355 (78.6) | 10 009 (98.1) | 0.64 |
Moderate (5–7) | 2531 (9.8) | 2374 (15.1) | 157 (1.5) | 0.51 |
Severe (0–4) | 1021 (3.9) | 983 (6.3) | 38 (0.4) | 0.33 |
Admission to registry hospital | 15 901 (60.3) | 13 153 (82.5) | 2748 (26.4) | 1.36 |
tPA on admission | 2275 (8.6) | 2255 (14.1) | 20 (0.2) | 0.56 |
Discharge medications |
Antiplatelet agents | 21 348 (81.0) | 12 907 (80.9) | 8441 (81.0) | 0.01 |
Warfarin | 4238 (16.1) | 3157 (19.8) | 1081 (10.4) | 0.27 |
All anticoagulants | 5422 (20.6) | 4215 (26.4) | 1207 (11.6) | 0.39 |
Antithrombotics | 24 192 (91.8) | 14 983 (93.9) | 9209 (88.4) | 0.20 |
CEA or CAS‡ |
At 1 yr | 229 (0.9) | 137 (0.9) | 92 (0.9) | 0.01 |
At 3 yr | 278 (1.3) | 170 (1.3) | 108 (1.3) | 0.01 |
At 5 yr | 239 (1.5) | 138 (1.4) | 101 (1.8) | 0.01 |