Guideline
Guideline for opioid therapy and chronic noncancer pain
Jason W. Busse, Samantha Craigie, David N. Juurlink, D. Norman Buckley, Li Wang, Rachel J. Couban, Thomas Agoritsas, Elie A. Akl, Alonso Carrasco-Labra, Lynn Cooper, Chris Cull, Bruno R. da Costa, Joseph W. Frank, Gus Grant, Alfonso Iorio, Navindra Persaud, Sol Stern, Peter Tugwell, Per Olav Vandvik and Gordon H. Guyatt
CMAJ May 08, 2017 189 (18) E659-E666; DOI: https://doi.org/10.1503/cmaj.170363
Jason W. Busse
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
DC PhDSamantha Craigie
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MScDavid N. Juurlink
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MD PhDD. Norman Buckley
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MDLi Wang
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
PhDRachel J. Couban
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MA MIStThomas Agoritsas
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MD PhDElie A. Akl
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MD PhDAlonso Carrasco-Labra
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
DDS MScLynn Cooper
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
BESChris Cull
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
Bruno R. da Costa
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
PT PhDJoseph W. Frank
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MD MPHGus Grant
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
AB LLB MDAlfonso Iorio
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MD PhDNavindra Persaud
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MD MScSol Stern
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MDPeter Tugwell
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MD MScPer Olav Vandvik
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MD PhDGordon H. Guyatt
The Michael G. DeGroote Institute for Pain Research and Care (Busse, Buckley, Couban, Craigie and Wang), Department of Anesthesia (Busse and Buckley), Department of Health Research Methods, Evidence, and Impact (Busse, Carrasco-Labra, Iorio and Guyatt), McMaster University, Hamilton, Ont.; University Hospitals of Geneva (Agoritsas), Geneva, Switzerland; American University of Beirut (Akl), Beirut, Lebanon; Canadian Pain Coalition (Cooper), Oshawa, Ont.; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry (Carrasco-Labra), University of Chile, Santiago, Chile; Inspire by Example, Canada (Cull); Institute of Primary Health Care (da Costa), University of Bern, Bern, Switzerland; VA Eastern Colorado Health Care System (Frank), Denver, Colo. and University of Colorado School of Medicine (Frank), Aurora, Colo.; College of Physicians and Surgeons of Nova Scotia (Grant), Halifax, NS; Departments of Medicine and Pediatrics (Juurlink), University of Toronto, Toronto, Ont.; Li Ka Shing Knowledge Institute (Persaud), St. Michael’s Hospital, Toronto, Ont.; Argus Medical Centre (Stern), Oakville, Ont.; Department of Medicine (Tugwell), University of Ottawa, Ottawa, Ont.; Innlandet Hospital Trust-Division Gjøvik (Vandvik), Norway
MD MScIn this issue
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Guideline for opioid therapy and chronic noncancer pain
Jason W. Busse, Samantha Craigie, David N. Juurlink, D. Norman Buckley, Li Wang, Rachel J. Couban, Thomas Agoritsas, Elie A. Akl, Alonso Carrasco-Labra, Lynn Cooper, Chris Cull, Bruno R. da Costa, Joseph W. Frank, Gus Grant, Alfonso Iorio, Navindra Persaud, Sol Stern, Peter Tugwell, Per Olav Vandvik, Gordon H. Guyatt
CMAJ May 2017, 189 (18) E659-E666; DOI: 10.1503/cmaj.170363
Guideline for opioid therapy and chronic noncancer pain
Jason W. Busse, Samantha Craigie, David N. Juurlink, D. Norman Buckley, Li Wang, Rachel J. Couban, Thomas Agoritsas, Elie A. Akl, Alonso Carrasco-Labra, Lynn Cooper, Chris Cull, Bruno R. da Costa, Joseph W. Frank, Gus Grant, Alfonso Iorio, Navindra Persaud, Sol Stern, Peter Tugwell, Per Olav Vandvik, Gordon H. Guyatt
CMAJ May 2017, 189 (18) E659-E666; DOI: 10.1503/cmaj.170363
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- Family Physician Perceptions of Their Role in Managing the Opioid Crisis
- Response to "Opioids for chronic pain"
- From pain treatment to opioid dependence: a qualitative study of the environmental influence on codeine use in UK adults
- Consider the economic burden for patients
- Recalling high-strength opioid formulations would cause harm
- Opioid Wisely
- High-strength opioid formulations: the case for a ministerial recall
- A perioperative approach to the opioid crisis
- What interventions are effective to taper opioids in patients with chronic pain?
- Contributions of prescribed and non-prescribed opioids to opioid related deaths: population based cohort study in Ontario, Canada
- The 2017 Canadian opioid guideline: already time for an overhaul
- The authors respond to "The 2017 Canadian opioid guideline: already time for an overhaul"
- Opioids for chronic pain
- Opioid prescribing and adverse events in opioid-naive patients treated by emergency physicians versus family physicians: a population-based cohort study
- Adverse effects of opioids for non-cancer pain
- Systematic review of systematic reviews for medical cannabinoids: Pain, nausea and vomiting, spasticity, and harms
- Management of osteoarthritis of the knee in younger patients
- An emergency response to the opioid overdose crisis in Canada: a regulated opioid distribution program
- Opioid use disorders as an emerging disability
- Opioid warning label
- Response to "Opioid warning label"
- Inconsistencies in the 2017 Canadian Guideline for Opioids for Chronic Noncancer Pain
- The authors respond to "Inconsistencies in the 2017 Canadian Guideline for Opioids for Chronic Noncancer Pain"
- Role of regulators in safe prescribing of opioids
- Sensible approaches to manage the current opioid crisis
- Response to "Role of regulators in safe prescribing of opioids"
- New Canadian guidance on opioid use for chronic pain: necessary but not sufficient
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