Occurrence of pregnancy and pregnancy outcomes during isotretinoin therapy

David Henry; Colin Dormuth; Brandace Winquist; Greg Carney; Shawn Bugden; Gary Teare; Linda E. Lévesque; Anick Bérard; J. Michael Paterson; Robert W. Platt

doi:10.1503/cmaj.151243

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Occurrence of pregnancy and pregnancy outcomes during isotretinoin therapy

David Henry, Colin Dormuth, Brandace Winquist, Greg Carney, Shawn Bugden, Gary Teare, Linda E. Lévesque, Anick Bérard, J. Michael Paterson and Robert W. Platt; for the CNODES (Canadian Network for Observational Drug Effect Studies) Investigators

CMAJ July 12, 2016 188 (10) 723-730; DOI: https://doi.org/10.1503/cmaj.151243

David Henry

Institute for Clinical Evaluative Sciences (Henry, Lévesque, Paterson), Toronto, Ont.; Institute of Health Policy, Management and Evaluation (Henry), University of Toronto, Toronto, Ont.; Faculty of Medicine (Dormuth, Carney), University of British Columbia, Vancouver, BC; Saskatchewan Health Quality Council (Winquist, Teare), Saskatoon, Sask.; College of Pharmacy (Bugden), Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.; Centre for Health Services and Policy Research (Lévesque), Queen’s University, Kingston, Ont.; Faculté de pharmacie (Bérard), Université de Montréal, Montréal, Qué.; Department of Family Medicine (Paterson), McMaster University, Hamilton, Ont.; Departments of Epidemiology and Biostatistics and of Pediatrics (Platt), McGill University, Montréal, Que.

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For correspondence: david.henry@ices.on.ca

Colin Dormuth

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Brandace Winquist

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Greg Carney

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Shawn Bugden

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Gary Teare

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Linda E. Lévesque

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Anick Bérard

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J. Michael Paterson

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Robert W. Platt

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Appendix 1: Diagnostic and procedural codes for high-specificity and high-sensitivity definitions of pregnancy (based on information for Saskatchewan)
Appendix 2: Details of ethics review approvals and British Columbia data sources
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(2016). Highlights. CMAJ, 188(10), 702. Accessed December 14, 2019. Retrieved from http://www.cmaj.ca/content/188/10/702.
Wilson, R. D. (2016). A preventable teratology: isotretinoin. CMAJ, 188(12), 901. Accessed December 14, 2019. https://doi.org/10.1503/cmaj.1150114.
Tan, J. K., & Shear, N. (2017). Oral isotretinoin: ensuring safe use while not limiting access to those who need it. CMAJ, 189(13), E510. Accessed December 14, 2019. https://doi.org/10.1503/cmaj.732920.

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Canadian Medical Association Journal: 188 (10)

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Vol. 188, Issue 10

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Occurrence of pregnancy and pregnancy outcomes during isotretinoin therapy

David Henry, Colin Dormuth, Brandace Winquist, Greg Carney, Shawn Bugden, Gary Teare, Linda E. Lévesque, Anick Bérard, J. Michael Paterson, Robert W. Platt

CMAJ Jul 2016, 188 (10) 723-730; DOI: 10.1503/cmaj.151243

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Occurrence of pregnancy and pregnancy outcomes during isotretinoin therapy

David Henry, Colin Dormuth, Brandace Winquist, Greg Carney, Shawn Bugden, Gary Teare, Linda E. Lévesque, Anick Bérard, J. Michael Paterson, Robert W. Platt

CMAJ Jul 2016, 188 (10) 723-730; DOI: 10.1503/cmaj.151243

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