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Practice

Peanut and fish allergy due to platelet transfusion in a child

Joyce Cheung Yee Ching, Wendy Lau, Barbara Hannach and Julia Elizabeth Mainwaring Upton
CMAJ September 08, 2015 187 (12) 905-907; DOI: https://doi.org/10.1503/cmaj.141407
Joyce Cheung Yee Ching
Department of Pediatrics (Ching), Rouge Valley Health System; Transfusion Medicine (Lau), Pediatric Laboratory Medicine, University of Toronto, Hospital for Sick Children; Canadian Blood Services (Lau, Hannach); Department of Pediatrics (Upton), Division of Clinical Immunology and Allergy, University of Toronto, Hospital for Sick Children, Toronto, Ont.
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Wendy Lau
Department of Pediatrics (Ching), Rouge Valley Health System; Transfusion Medicine (Lau), Pediatric Laboratory Medicine, University of Toronto, Hospital for Sick Children; Canadian Blood Services (Lau, Hannach); Department of Pediatrics (Upton), Division of Clinical Immunology and Allergy, University of Toronto, Hospital for Sick Children, Toronto, Ont.
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Barbara Hannach
Department of Pediatrics (Ching), Rouge Valley Health System; Transfusion Medicine (Lau), Pediatric Laboratory Medicine, University of Toronto, Hospital for Sick Children; Canadian Blood Services (Lau, Hannach); Department of Pediatrics (Upton), Division of Clinical Immunology and Allergy, University of Toronto, Hospital for Sick Children, Toronto, Ont.
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Julia Elizabeth Mainwaring Upton
Department of Pediatrics (Ching), Rouge Valley Health System; Transfusion Medicine (Lau), Pediatric Laboratory Medicine, University of Toronto, Hospital for Sick Children; Canadian Blood Services (Lau, Hannach); Department of Pediatrics (Upton), Division of Clinical Immunology and Allergy, University of Toronto, Hospital for Sick Children, Toronto, Ont.
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    Figure 1:

    Skin prick testing with multiple food extracts shortly after anaphylactic reaction to peanuts in 8-year-old boy who had received blood products. Results show strongly positive IgE-mediated reactions to peanut, tree nut mix, fish mix and salmon.

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    Figure 2:

    Timeline of events in an 8-year-old patient with peanut and fish allergy from platelet transfusion. Pooled platelets suspended in 200 mL of plasma from an atopic donor with allergies to peanuts, tree nuts, shellfish and all fish were transfused on day 4. Allergic reactions occurred 9 and 13 days after this transfusion. Other platelet transfusions included plasma from donors without allergies, and SAGM red blood cell transfusion had less than 5 mL of plasma from a donor with an unknown allergy status. SAGM = saline–adenine–glucose–mannitol. *Requested as add-on measurement in sample drawn on day 15 after reaction on day 17.

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Canadian Medical Association Journal: 187 (12)
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Vol. 187, Issue 12
8 Sep 2015
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Peanut and fish allergy due to platelet transfusion in a child
Joyce Cheung Yee Ching, Wendy Lau, Barbara Hannach, Julia Elizabeth Mainwaring Upton
CMAJ Sep 2015, 187 (12) 905-907; DOI: 10.1503/cmaj.141407

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Peanut and fish allergy due to platelet transfusion in a child
Joyce Cheung Yee Ching, Wendy Lau, Barbara Hannach, Julia Elizabeth Mainwaring Upton
CMAJ Sep 2015, 187 (12) 905-907; DOI: 10.1503/cmaj.141407
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