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Letters

Quinine and leg cramps

Hans D. Katzberg and Ari Breiner
CMAJ July 14, 2015 187 (10) 757; DOI: https://doi.org/10.1503/cmaj.1150039
Hans D. Katzberg
Division of Neurology (Katzberg, Breiner) University of Toronto, Toronto, Ont.
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Ari Breiner
Division of Neurology (Katzberg, Breiner) University of Toronto, Toronto, Ont.
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We would like to respond to Hogan’s commentary,1 which states that quinine is not a safe drug in the treatment of muscle cramps. Hogan points out that nonpharmacologic and other pharmacologic options should be tried before prescribing quinine sulphate.1 But, it is important to note that our previously published recommendations and guidelines2 maintain a clear role for quinine when prescribed by physicians, and when adequate counselling is given to patients and adequate monitoring is in place. Simply calling a drug unsafe may lead to bans similar to those enacted in the United States, which severely limit options for neuromuscular clinicians who care for patients with disabling and terminal conditions such as amyotrophic lateral sclerosis.

References

  1. ↵
    1. Hogan DB
    . Quinine: not a safe drug for treating nocturnal leg cramps. CMAJ 2015;187:237–8.
    OpenUrlFREE Full Text
  2. ↵
    1. Katzberg HD,
    2. Khan A,
    3. So YT
    . Assessment: symptomatic treatment for muscle cramps (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2010;74:691–6.
    OpenUrlCrossRefPubMed
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Canadian Medical Association Journal: 187 (10)
CMAJ
Vol. 187, Issue 10
14 Jul 2015
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Quinine and leg cramps
Hans D. Katzberg, Ari Breiner
CMAJ Jul 2015, 187 (10) 757; DOI: 10.1503/cmaj.1150039

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Quinine and leg cramps
Hans D. Katzberg, Ari Breiner
CMAJ Jul 2015, 187 (10) 757; DOI: 10.1503/cmaj.1150039
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