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Research

Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise

Holger J. Schünemann, Wojtek Wiercioch, Itziar Etxeandia, Maicon Falavigna, Nancy Santesso, Reem Mustafa, Matthew Ventresca, Romina Brignardello-Petersen, Kaja-Triin Laisaar, Sérgio Kowalski, Tejan Baldeh, Yuan Zhang, Ulla Raid, Ignacio Neumann, Susan L. Norris, Judith Thornton, Robin Harbour, Shaun Treweek, Gordon Guyatt, Pablo Alonso-Coello, Marge Reinap, Jan Brožek, Andrew Oxman and Elie A. Akl
CMAJ February 18, 2014 186 (3) E123-E142; DOI: https://doi.org/10.1503/cmaj.131237
Holger J. Schünemann
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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  • For correspondence: [email protected]
Wojtek Wiercioch
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Itziar Etxeandia
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Maicon Falavigna
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Nancy Santesso
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Reem Mustafa
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Matthew Ventresca
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Romina Brignardello-Petersen
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Kaja-Triin Laisaar
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Sérgio Kowalski
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
MD PhD
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Tejan Baldeh
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Yuan Zhang
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
BHSc
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Ulla Raid
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Ignacio Neumann
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Susan L. Norris
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Judith Thornton
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Robin Harbour
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Shaun Treweek
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Gordon Guyatt
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Pablo Alonso-Coello
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Marge Reinap
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Jan Brožek
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Andrew Oxman
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Elie A. Akl
Department of Clinical Epidemiology and Biostatistics (Schünemann, Wiercioch, Etxeandia, Falavigna, Santesso, Mustafa, Ventresca, Kowalski, Baldeh, Zhang, Neumann, Guyatt, Brožek, Akl) and Department of Medicine (Schünemann, Brošek, Guyatt), McMaster University, Hamilton, Ont.; Department für Medizinische Biometrie und Medizinische Informatik (Schünemann, Brošek), Universitätsklinikum Freiburg, Freiburg, Germany; Department of Community Health Sciences (Ventresca), Brock University, St. Catharines, Ont.; Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon; Department of Medicine (Akl), University at Buffalo, New York State University, Buffalo, NY; Department of Internal Medicine and Nephrology (Mustafa), University of Missouri–Kansas City, Kansas City, Mo.; Oregon Health and Science University (Norris), Portland, Ore.; National Institute of Science and Technology for Health Technology Assessment (Falavigna), Federal University of Rio Grande do Sul, and Hospital Moinhos de Ventos, Porto Alegre, Brazil; Department of Internal Medicine (Neumann), Pontificia Universidad Católica de Chile, Santiago, Chile; Estonian Health Insurance Fund (Raid), Estonian Country Office of the World Health Organization (Reinap), Tallinn, Estonia; University of Tartu (Laisaar), Tartu, Estonia; University of Aberdeen (Treweek), Aberdeen, UK; National Institute for Health and Care Excellence (Thornton), London, UK; Scottish Intercollegiate Guideline Network (Harbour), Healthcare Improvement Scotland, Edinburgh, UK; Institute of Health Policy, Management and Evaluation (Brignardello-Petersen), University of Toronto, Toronto, Ont.; Faculty of Dentistry (Brignardello-Petersen), University of Chile, Santiago, Chile; and Norwegian Knowledge Center for the Health Services (Oxman), Oslo, Norway
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Canadian Medical Association Journal: 186 (3)
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18 Feb 2014
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Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise
Holger J. Schünemann, Wojtek Wiercioch, Itziar Etxeandia, Maicon Falavigna, Nancy Santesso, Reem Mustafa, Matthew Ventresca, Romina Brignardello-Petersen, Kaja-Triin Laisaar, Sérgio Kowalski, Tejan Baldeh, Yuan Zhang, Ulla Raid, Ignacio Neumann, Susan L. Norris, Judith Thornton, Robin Harbour, Shaun Treweek, Gordon Guyatt, Pablo Alonso-Coello, Marge Reinap, Jan Brožek, Andrew Oxman, Elie A. Akl
CMAJ Feb 2014, 186 (3) E123-E142; DOI: 10.1503/cmaj.131237

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Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise
Holger J. Schünemann, Wojtek Wiercioch, Itziar Etxeandia, Maicon Falavigna, Nancy Santesso, Reem Mustafa, Matthew Ventresca, Romina Brignardello-Petersen, Kaja-Triin Laisaar, Sérgio Kowalski, Tejan Baldeh, Yuan Zhang, Ulla Raid, Ignacio Neumann, Susan L. Norris, Judith Thornton, Robin Harbour, Shaun Treweek, Gordon Guyatt, Pablo Alonso-Coello, Marge Reinap, Jan Brožek, Andrew Oxman, Elie A. Akl
CMAJ Feb 2014, 186 (3) E123-E142; DOI: 10.1503/cmaj.131237
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