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Research

Rates of hemorrhage during warfarin therapy for atrial fibrillation

Tara Gomes, Muhammad M. Mamdani, Anne M. Holbrook, J. Michael Paterson, Chelsea Hellings and David N. Juurlink
CMAJ February 05, 2013 185 (2) E121-E127; DOI: https://doi.org/10.1503/cmaj.121218
Tara Gomes
The Leslie Dan Faculty of Pharmacy (Gomes, Mamdani) and the Department of Health Policy, Management, and Evaluation (Juurlink, Mamdani, Paterson), University of Toronto; the Institute for Clinical Evaluative Sciences (Juurlink, Paterson, Hellings, Mamdani); the Sunnybrook Research Institute (Juurlink); and the Keenan Research Centre of the Li Ka Shing Knowledge Institute (Mamdani), St. Michael’s Hospital, Toronto, Ont.; the Department of Family Medicine (Paterson) and Division of Clinical Pharmacology & Therapeutics (Holbrook), McMaster University; and the Centre for Evaluation of Medicines (Holbrook, Paterson), St. Joseph’s Healthcare, Hamilton, Ont.
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  • For correspondence: tara.gomes@ices.on.ca
Muhammad M. Mamdani
The Leslie Dan Faculty of Pharmacy (Gomes, Mamdani) and the Department of Health Policy, Management, and Evaluation (Juurlink, Mamdani, Paterson), University of Toronto; the Institute for Clinical Evaluative Sciences (Juurlink, Paterson, Hellings, Mamdani); the Sunnybrook Research Institute (Juurlink); and the Keenan Research Centre of the Li Ka Shing Knowledge Institute (Mamdani), St. Michael’s Hospital, Toronto, Ont.; the Department of Family Medicine (Paterson) and Division of Clinical Pharmacology & Therapeutics (Holbrook), McMaster University; and the Centre for Evaluation of Medicines (Holbrook, Paterson), St. Joseph’s Healthcare, Hamilton, Ont.
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Anne M. Holbrook
The Leslie Dan Faculty of Pharmacy (Gomes, Mamdani) and the Department of Health Policy, Management, and Evaluation (Juurlink, Mamdani, Paterson), University of Toronto; the Institute for Clinical Evaluative Sciences (Juurlink, Paterson, Hellings, Mamdani); the Sunnybrook Research Institute (Juurlink); and the Keenan Research Centre of the Li Ka Shing Knowledge Institute (Mamdani), St. Michael’s Hospital, Toronto, Ont.; the Department of Family Medicine (Paterson) and Division of Clinical Pharmacology & Therapeutics (Holbrook), McMaster University; and the Centre for Evaluation of Medicines (Holbrook, Paterson), St. Joseph’s Healthcare, Hamilton, Ont.
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J. Michael Paterson
The Leslie Dan Faculty of Pharmacy (Gomes, Mamdani) and the Department of Health Policy, Management, and Evaluation (Juurlink, Mamdani, Paterson), University of Toronto; the Institute for Clinical Evaluative Sciences (Juurlink, Paterson, Hellings, Mamdani); the Sunnybrook Research Institute (Juurlink); and the Keenan Research Centre of the Li Ka Shing Knowledge Institute (Mamdani), St. Michael’s Hospital, Toronto, Ont.; the Department of Family Medicine (Paterson) and Division of Clinical Pharmacology & Therapeutics (Holbrook), McMaster University; and the Centre for Evaluation of Medicines (Holbrook, Paterson), St. Joseph’s Healthcare, Hamilton, Ont.
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Chelsea Hellings
The Leslie Dan Faculty of Pharmacy (Gomes, Mamdani) and the Department of Health Policy, Management, and Evaluation (Juurlink, Mamdani, Paterson), University of Toronto; the Institute for Clinical Evaluative Sciences (Juurlink, Paterson, Hellings, Mamdani); the Sunnybrook Research Institute (Juurlink); and the Keenan Research Centre of the Li Ka Shing Knowledge Institute (Mamdani), St. Michael’s Hospital, Toronto, Ont.; the Department of Family Medicine (Paterson) and Division of Clinical Pharmacology & Therapeutics (Holbrook), McMaster University; and the Centre for Evaluation of Medicines (Holbrook, Paterson), St. Joseph’s Healthcare, Hamilton, Ont.
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David N. Juurlink
The Leslie Dan Faculty of Pharmacy (Gomes, Mamdani) and the Department of Health Policy, Management, and Evaluation (Juurlink, Mamdani, Paterson), University of Toronto; the Institute for Clinical Evaluative Sciences (Juurlink, Paterson, Hellings, Mamdani); the Sunnybrook Research Institute (Juurlink); and the Keenan Research Centre of the Li Ka Shing Knowledge Institute (Mamdani), St. Michael’s Hospital, Toronto, Ont.; the Department of Family Medicine (Paterson) and Division of Clinical Pharmacology & Therapeutics (Holbrook), McMaster University; and the Centre for Evaluation of Medicines (Holbrook, Paterson), St. Joseph’s Healthcare, Hamilton, Ont.
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Data supplements

  • Online Appendix

    • Appendix 1: Diagnosis codes used to define hemorrhage outcomes and rates of prothrombin time tests 7 and 14 days before patient index date

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  • (2013). Highlights. CMAJ, 185(2), 105. Accessed May 21, 2022. Retrieved from http://www.cmaj.ca/content/185/2/105.
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Canadian Medical Association Journal: 185 (2)
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5 Feb 2013
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Rates of hemorrhage during warfarin therapy for atrial fibrillation
Tara Gomes, Muhammad M. Mamdani, Anne M. Holbrook, J. Michael Paterson, Chelsea Hellings, David N. Juurlink
CMAJ Feb 2013, 185 (2) E121-E127; DOI: 10.1503/cmaj.121218

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Rates of hemorrhage during warfarin therapy for atrial fibrillation
Tara Gomes, Muhammad M. Mamdani, Anne M. Holbrook, J. Michael Paterson, Chelsea Hellings, David N. Juurlink
CMAJ Feb 2013, 185 (2) E121-E127; DOI: 10.1503/cmaj.121218
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