Effects of intensive blood pressure lowering on the progression of chronic kidney disease: a systematic review and meta-analysis

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden

The George Institute for Global Health (Lv, Ehteshami, Jun, Foote, Rodgers, Perkovic), The University of Sydney, Sydney, Australia; Renal Division, Department of medicine (Lv, Zhang, Wang), Peking University First Hospital, Beijing, China; Tufts Medical Center (Sarnak, Tighiouart), Boston, Mass.; the Department of Medicine and Clinical Science Graduate School of Medical Sciences (Ninomiya), Kyushu University, Japan; the Centre for Kidney Research (Strippoli), The Children’s Hospital at Westmead, School of Public Health, The University of Sydney, Sydney, Australia; the Department of Pharmacology and Epidemiology (Strippoli), Mario Negri Sud Consortium, S Maria Imbaro, Chieti, Italy; and DIAVERUM Medical-Scientific Office (Strippoli), Lund, Sweden