Age, yr | 77.4 ± 7.9 | 77.0 ± 7.5 | 0.6 |
66–75 | 65 (45.1) | 654 (46.4) | 0.9 |
76–85 | 54 (37.5) | 534 (37.9) | |
≥ 86 | 25 (17.4) | 221 (15.7) | |
Female sex | 68 (47.2) | 671 (47.6) | |
Study antibiotic received during the 30-d period before admission |
Clarithromycin (reference) | 27 (18.8) | 431 (30.6) | 0.03 |
Cefuroxime axetil | 14 (9.7) | 141 (10.0) | |
Ciprofloxacin | 54 (37.5) | 483 (34.3) | |
Levofloxacin | 23 (16.0) | 180 (12.8) | |
Moxifloxacin | 26 (18.1) | 174 (12.3) | |
Any study antibiotic received 31–365 d before admission | 70 (48.6) | 655 (46.5) | 0.6 |
Neighbourhood income quintile |
1 (lowest) | 21 (14.6) | 285 (20.2) | 0.06 |
2 | 42 (29.2) | 303 (21.5) | |
3 | 36 (25.0) | 280 (19.8) | |
4 | 24 (16.6) | 288 (20.4) | |
5 (highest) | 20 (13.9) | 246 (17.5) | |
Resident in a nursing home | 20 (13.9) | 162 (11.5) | 0.4 |
No. of prescription drugs received in the preceding year | 14.1 ± 6.7 | 12.0 ± 6.1 | < 0.001 |
No. of outpatient visits to a physician in the preceding year | 15.7 ± 11.0 | 13.4 ± 9.9 | 0.009 |
Diabetes mellitus | 53 (36.8) | 405 (28.7) | 0.04 |
Alcohol dependence | 6 (4.2) | 30 (2.1) | 0.1 |
Receipt of sulfamethoxazole– trimethoprim in the 90-d period before admission | 9 (6.3) | 42 (3.0) | 0.04 |
Receipt of allopurinol in the 90-d period before admission | 9 (6.3) | 52 (3.7) | 0.1 |
Receipt of a hepatotoxic drug in the 90-d period before admission† | 8 (5.6) | 40 (2.8) | 0.07 |