Figure 1:
Numbers of carbapenemase-producing Enterobacteriaceae referred from laboratories in the United Kingdom to the Health Protection Agency’s national reference laboratory between 2003 and 2009. The predominant gene is blaNDM-1. The other group includes diverse producers of carbapenemases, Klebsiella pneumoniae carbapenemase, oxacillinase-48, IMP and VIM enzymes. Reprinted from Kumarasamy KK, Toleman MA, Walsh TR, et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis 2010;10:597–602.