Skip to main content

Main menu

  • Home
  • Content
    • Current issue
    • Past issues
    • Early releases
    • Collections
    • Sections
    • Blog
    • Infographics & illustrations
    • Podcasts
    • COVID-19 articles
    • Obituary notices
  • Authors & Reviewers
    • Overview for authors
    • Submission guidelines
    • Submit a manuscript
    • Forms
    • Editorial process
    • Editorial policies
    • Peer review process
    • Publication fees
    • Reprint requests
    • Open access
    • Patient engagement
  • Physicians & Subscribers
    • Benefits for Canadian physicians
    • CPD Credits for CMA Members
    • Subscribe to CMAJ Print
    • Subscription prices
    • Obituary notices
  • Alerts
    • Email alerts
    • RSS
  • JAMC
    • À propos
    • Numéro en cours
    • Archives
    • Sections
    • Abonnement
    • Alertes
    • Trousse média 2023
    • Avis de décès
  • CMAJ JOURNALS
    • CMAJ Open
    • CJS
    • JAMC
    • JPN

User menu

Search

  • Advanced search
CMAJ
  • CMAJ JOURNALS
    • CMAJ Open
    • CJS
    • JAMC
    • JPN
CMAJ

Advanced Search

  • Home
  • Content
    • Current issue
    • Past issues
    • Early releases
    • Collections
    • Sections
    • Blog
    • Infographics & illustrations
    • Podcasts
    • COVID-19 articles
    • Obituary notices
  • Authors & Reviewers
    • Overview for authors
    • Submission guidelines
    • Submit a manuscript
    • Forms
    • Editorial process
    • Editorial policies
    • Peer review process
    • Publication fees
    • Reprint requests
    • Open access
    • Patient engagement
  • Physicians & Subscribers
    • Benefits for Canadian physicians
    • CPD Credits for CMA Members
    • Subscribe to CMAJ Print
    • Subscription prices
    • Obituary notices
  • Alerts
    • Email alerts
    • RSS
  • JAMC
    • À propos
    • Numéro en cours
    • Archives
    • Sections
    • Abonnement
    • Alertes
    • Trousse média 2023
    • Avis de décès
  • Visit CMAJ on Facebook
  • Follow CMAJ on Twitter
  • Follow CMAJ on Pinterest
  • Follow CMAJ on Youtube
  • Follow CMAJ on Instagram
Highlights

Highlights

CMAJ July 13, 2010 182 (10) 1009;
  • Article
  • Figures & Tables
  • Responses
  • Metrics
  • PDF
Loading

Pregnancy and antidepressants

The use of antidepressants during pregnancy was associated with an increased risk of spontaneous abortion. Nakhai-Pour and colleagues come to this conclusion from their nested case–control study based on data from the Quebec Pregnancy Registry. Physicians who care for women of child-bearing age, including those who are pregnant, may wish to discuss the risks and benefits of taking antidepressants with their patients, say the authors. See Research, page 1031

If there is a true increased risk of spontaneous abortion associated with the use of antidepressants during pregnancy, it is small, says Einarson. See Commentary, page 1017

Figure
  • Download figure
  • Open in new tab
  • Download powerpoint

Image courtesy of © 2010 Jupiterimages Corp.

Is it myocardial infarction?

The thrombolysis in myocardial infarction (TIMI) risk score can be used in emergency departments to identify patients with chest pain who are at high or low risk of acute coronary syndromes. This conclusion is based on a systematic review of 10 cohort studies with over 17 000 patients. The TIMI score can be used to aid clinical decisions, say the authors, but the score is not accurate enough to be used as the sole method for planning care. See Research, page 1039

Developing, reporting and evaluating guidelines

This is the first of two studies designed to improve the AGREE (Appraisal of Guidelines, Research and Evaluation) instrument used to develop, report and evaluate practice guidelines. Brouwers and colleagues analyze the performance of a new seven-point response scale, explore the usefulness of the AGREE items and systematically identify ways in which the items and supporting document could be improved. See Research, page 1045

Figure
  • Download figure
  • Open in new tab
  • Download powerpoint

Image courtesy of © 2010 Jupiterimages Corp.

Heat-related illnesses

People over the age of 60 years and those with obesity, cardiovascular disease, pulmonary disease or long-standing diabetes are at increased risk of heat-related illness during heat waves. This vulnerability is increased in those who have a homebound lifestyle, lack of contact with other people and have decreased mobility. See Reviews, page 1053

Figure
  • Download figure
  • Open in new tab
  • Download powerpoint

Image courtesy of © 2010 Jupiterimages Corp.

Frozen plasma

Pinkerton and Callum lament the poor quality of evidence that underpins guidelines for the use of frozen plasma in clinical practice. See Commentary, page 1019

Sickle cell disease, fever and headache

A five-year-old girl with sickle cell disease who presented with a two-day history of left frontal headache and mild fever later develops facial edema. She has signs of meningeal irritation and tenderness over the dorsal vertebrae. Which tests should you perform? What is your diagnosis?See Practice, page 1069

Figure
  • Download figure
  • Open in new tab
  • Download powerpoint

Figure.

Janeway lesions

A 52-year-old man presented with fever, lightheadedness and myalgia of one week’s duration and a previous history of endocarditis. He had Janeway lesions on his big toe. See Clinical images, page 1075

PreviousNext
Back to top

In this issue

Canadian Medical Association Journal: 182 (10)
CMAJ
Vol. 182, Issue 10
13 Jul 2010
  • Table of Contents
  • Index by author

Article tools

Respond to this article
Print
Download PDF
Article Alerts
To sign up for email alerts or to access your current email alerts, enter your email address below:
Email Article

Thank you for your interest in spreading the word on CMAJ.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Highlights
(Your Name) has sent you a message from CMAJ
(Your Name) thought you would like to see the CMAJ web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Highlights
CMAJ Jul 2010, 182 (10) 1009;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
‍ Request Permissions
Share
Highlights
CMAJ Jul 2010, 182 (10) 1009;
Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like

Jump to section

  • Article
  • Figures & Tables
  • Responses
  • Metrics
  • PDF

Related Articles

  • Use of antidepressants during pregnancy and the risk of spontaneous abortion
  • Antidepressants and pregnancy: complexities of producing evidence-based information
  • Diagnostic accuracy of the TIMI risk score in patients with chest pain in the emergency department: a meta-analysis
  • Development of the AGREE II, part 1: performance, usefulness and areas for improvement
  • Heat stress in older individuals and patients with common chronic diseases
  • Rationalizing the clinical use of frozen plasma
  • Meningeal signs and facial edema in a child with sickle cell disease
  • Janeway lesions
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Highlights
  • Highlights
  • Highlights
Show more Highlights

Similar Articles

 

View Latest Classified Ads

Content

  • Current issue
  • Past issues
  • Collections
  • Sections
  • Blog
  • Podcasts
  • Alerts
  • RSS
  • Early releases

Information for

  • Advertisers
  • Authors
  • Reviewers
  • CMA Members
  • CPD credits
  • Media
  • Reprint requests
  • Subscribers

About

  • General Information
  • Journal staff
  • Editorial Board
  • Advisory Panels
  • Governance Council
  • Journal Oversight
  • Careers
  • Contact
  • Copyright and Permissions
CMAJ Group

Copyright 2023, CMA Impact Inc. or its licensors. All rights reserved. ISSN 1488-2329 (e) 0820-3946 (p)

All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Canadian Medical Association or its subsidiaries.

To receive any of these resources in an accessible format, please contact us at CMAJ Group, 500-1410 Blair Towers Place, Ottawa ON, K1J 9B9; p: 1-888-855-2555; e: cmajgroup@cmaj.ca

CMA Civility, Accessibility, Privacy

 

Powered by HighWire