Background Recent studies have reported a trend toward earlier initiation of dialysis (ie, at
higher levels of glomerular filtration rate) and an association between early initiation and …

Abstract Background/Aims: The association of the timing of dialysis initiation with mortality is
controversial. We conducted a meta-analysis to determine the relationship between the risk …

Background: Current recommendations for initiating dialysis therapy are based on level of
kidney function and clinical evidence of uremia. Several studies reported no benefit in …

Clinical experience suggests a heightened risk associated with the transition to
maintenance dialysis but few national studies have systematically examined early mortality …

Starting patients on dialysis early has been increasing in incidence in several countries.
However, some studies have questioned its utility, finding a counter-intuitive effect of …

Background. Outcomes are a major metric for evaluating effectiveness of dialysis.
Comparisons between different populations reveal significant variation. In addition, the …

The estimated glomerular filtration rate (eGFR) at dialysis initiation has been rising.
Observational studies suggest harm, but may be confounded by unmeasured factors. As …

Background Several observational studies of hemodialysis patients show an association
between early dialysis therapy initiation and increased mortality. Few studies have …

In their study based on data from the Dialysis Outcomes and Practice Patterns Study
(DOPPS) census database, including 86,886 hemodialysis patients from 11 countries …

Despite the availability of clinical guidelines for the timing of dialysis initiation in both the
United States and Canada, patients continue to start dialysis at very low levels of predicted …