Human papillomavirus in oropharyngeal cancer in Canada: analysis of 5 comprehensive cancer centres using multiple imputation

S Habbous, KP Chu, H Lau, M Schorr, M Belayneh… - Cmaj, 2017 - Can Med Assoc
BACKGROUND: The incidence of oropharyngeal cancer has risen over the past 2 decades.
This rise has been attributed to human papillomavirus (HPV), but information on temporal …

The changing incidence of human papillomavirus-associated oropharyngeal cancer using multiple imputation from 2000 to 2010 at a Comprehensive Cancer Centre

S Habbous, KP Chu, X Qiu, A La Delfa, LTG Harland… - Cancer …, 2013 - Elsevier
Introduction Human papillomavirus (HPV) is a risk and prognostic factor for oropharyngeal
cancer (OPC). Determining whether the incidence of HPV-associated OPC is rising informs …

[HTML][HTML] Evaluation of p16INK4a expression as a single marker to select patients with HPV-driven oropharyngeal cancers for treatment de-escalation

S Wagner, ES Prigge, N Wuerdemann, H Reder… - British journal of …, 2020 - nature.com
Background A remarkably better prognosis is associated with oropharyngeal squamous cell
carcinomas (OPSCC) driven by human papillomaviruses (HPV) compared with HPV …

[HTML][HTML] Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data …

H Mehanna, M Taberna, C Von Buchwald… - The Lancet …, 2023 - thelancet.com
Background p16 INK4a (p16) immunohistochemistry is the most widely used biomarker
assay for inferring HPV causation in oropharyngeal cancer in clinical and trial settings …

[HTML][HTML] The prevalence of human papillomavirus in oropharyngeal cancer in a New Zealand population

R Lucas-Roxburgh, J Benschop, B Lockett… - PLoS …, 2017 - journals.plos.org
Background The incidence of oropharyngeal cancer (OPC) in New Zealand (NZ) has more
than doubled over the last 14 years with 126 cases in 2010. Overseas studies have shown …

Geographic variation in human papillomavirus–related oropharyngeal cancer: Data from 4 multinational randomized trials

H Mehanna, N Franklin, N Compton, M Robinson… - Head & …, 2016 - Wiley Online Library
Background There are variations in the proportions of head and neck cancers caused by the
human papillomavirus (HPV) between countries and regions. It is unclear if these are true …

Increasing prevalence of HPV in oropharyngeal carcinoma suggests adaptation of p16 screening in Southeast Asia

I Argirion, KR Zarins, J McHugh, RL Cantley… - Journal of Clinical …, 2020 - Elsevier
Background Human papillomavirus (HPV) is etiologically linked to increasing oropharyngeal
squamous cell carcinoma (OPSCC) rates in the Western world. However, the role of HPV in …

[HTML][HTML] Human Papillomavirus-associated oropharyngeal cancer: an observational study of diagnosis, prevalence and prognosis in a UK population

M Evans, R Newcombe, A Fiander, J Powell, M Rolles… - BMC cancer, 2013 - Springer
Abstract Background The incidence of Human Papillomavirus (HPV) associated
oropharyngeal cancer (OPC) is increasing. HPV-associated OPC appear to have better …

High prevalence of discordant human papillomavirus and p16 oropharyngeal squamous cell carcinomas in an African American cohort

JC Liu, S Parajuli, E Blackman, D Gibbs, A Ellis… - Head & …, 2016 - Wiley Online Library
Background Most studies on human papillomavirus (HPV)‐associated oropharyngeal
squamous cell carcinoma (SCC) have been performed on white Americans. Our study …

[HTML][HTML] Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status: a European Multicentre Study (OroGrams)

C Grønhøj, DH Jensen, C Dehlendorff… - British Journal of …, 2018 - nature.com
Background The proxy marker for human papillomavirus (HPV), p16, is included in the new
AJCC 8th/UICC 8th staging system, but due to incongruence between p16 status and HPV …