I'm 25 years old. In my fourth year of university, I started to get numbness and tingling on the
soles of my feet. It slowly progressed up my legs. Getting to a diagnosis took months. I went …

A 47-year-old woman was seen in the rheumatology clinic because of numbness and pain
in the legs, which had begun 2 years earlier, intermittent swelling of the legs, and a rash …

A 47 year old male with a history of obesity, pulmonary embolus two years prior with a
completed course of rivaroxaban, and obstructive sleep apnea presents to the emergency …

Diagnosing One Letter at a Time | NEJM Skip to main content NEJM Group Follow Us Facebook
Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your knowledge …

A 14-year-old boy was referred by the rheumatology department to our orthopaedic service
for evaluation of new-onset left knee pain and swelling during the past 2 months. The patient …

66-YEAR-OLD WOMAN presents with progressive, painless weakness of the proximal legs,
which began 2 years ago. The onset was gradual: at first she had difficulty standing from a …

CASE▶ marie c, a 75-year-old asian woman, reports weakness in her legs and arms with
unsteadiness when walking. She has a vague but persistent ache in her large muscles. her …

A gentleman in his late 40s developed a “pins and needles” sensation and numbness in his
left hand that was exacerbated by leaning on his left arm or hyperextending his neck. The …

A 9-year-old girl presented to her pediatrician with 2 months of right knee pain with insidious
onset and no trauma. She was an active, multisport athlete. A diagnosis of overuse tendinitis …

A Man with Pain and Erythema of the Left Hand A 22-year-old man was admitted with pain
and erythema of the left hand. On the day of admission, he awoke with pain and swelling of …