How should this patient be evaluated further? a. Bone marrow aspiration and biopsy b. Skin
biopsy of the eruption c. Further autoimmune work-up including repeat rheumatoid factor …

Dear Editor, A 75-year-old Japanese woman was admitted to our hospital with epigastric
pain. Prior to the admission, she had experienced flu-like symptoms for 1 week. She also …

A previously healthy 47-year-old man presented with 3 weeks of bilateral hand numbness,
tingling, cyanosis, and newly onset lower extremity edema and petechiae. On examination …

We conducted a retrospective analysis of the clinical features of 20 patients with severe
eosinophilia at our institution, including 10 cases of hypereosinophilic syndrome (HES)(5 …

A 79-year-old man presented with marked, persistent hypereosinophilia (HE). Peripheral
blood (PB) counts showed leukocytosis (27.0× 10 9/L) with 98% eosinophils in PB smear …

A previously healthy 47-year-old man presented with 3 weeks of bilateral hand numbness,
tingling, cyanosis, and newly onset lower extremity edema and petechiae. On examination …

Hypereosinophilic syndromes are a wide group of entities. We present a 24-year-old-male
with left lower quadrant abdominal pain, elevated eosinophil counts and splenomegaly …

Hypereosinophilic syndromes (HES) are a heterogeneous group of disorders characterized
by marked peripheral blood and tissue eosinophilia resulting in end-stage organ damage …

Hypereosinophilic syndrome (HES) was diagnosed in December 2000 in a 43-year-old man
on the basis of persistent eosinophilia (11.7 x 109/L) and a normal karyotype of the bone …

Introduction Idiopathic hypereosinophilic syndrome is defined as persistently elevated
peripheral blood absolute eosinophil count of more than 1.5× 109/L for at least six months …