Background: It has been suggested that changes to the immune system could be a factor in
age-related conditions such as Alzheimer's disease. Our objective was to examine the …

ABSTRACT A growing literature supports a protective association between vaccines
targeting an array of pathogens (eg, influenza, pneumococcus, herpes zoster) and the risk of …

Introduction Vaccination against peptides specific to Alzheimer disease may generate an
immune response that could help inhibit disease and symptom progression. Methods …

Vaccination of APP transgenic mice with Aβ has been shown to prevent amyloid deposits. A
clinical trial of Aβ vaccination in Alzheimer's disease (AD) was halted due to serious …

Background Multiple types of vaccinations are associated with lower risk for dementia, but it
is not known if receiving more than one vaccination type is associated with a greater …

Abstract Background Two Taiwan based studies indicated influenza vaccinations are
associated with lower risk for dementia in patient cohorts with chronic disease. We …

Studies in transgenic mouse models of Alzheimer's disease suggested the potential for a
vaccine development. However, some patients in the human clinical trials developed …

The pathological hallmarks of Alzheimer's disease (AD) include β-amyloid (Aβ) plaques,
dystrophic neurites and neurofibrillary pathology, which eventually result in the …

Background Common vaccinations may have impacts on dementia risk, but current
evidence is inconsistent. We therefore investigated the association between vaccinations …

Background Observational studies suggesting that immunizations strongly decrease the risk
of dementia had several methodological limitations. We assessed whether common …