Quality of use of parenteral metronidazole therapy in a teaching hospital

PJ Jewesson, RL Bachand, GA Bell… - Canadian Medical …, 1985 - ncbi.nlm.nih.gov
The recent release, relatively high cost and potential adverse effects of parenterally
administered metronidazole prompted a quality-of-use audit at a 1000-bed teaching …

Intravenous metronidazole: a drug utilization review in a community hospital.

D Nessim - The Canadian Journal of Hospital Pharmacy, 1987 - europepmc.org
The recent release, relatively high cost and extensive usage of intravenous metronidazole,
in a 690-bed community hospital, prompted a drug utilization review of this antimicrobial …

[CITATION][C] Serum metronidazole levels following rectal administration

IF Lane, RW Pulvertaft, WG Hewitt - Journal of Antimicrobial …, 1981 - academic.oup.com
Sir, The safety and efficacy of metronidazole in the treatment of severe anaerobic infections
is well established (Ingham, Selkon & Hale, 1975). Recently much interest has been …

Failure of single-dose metronidazole prophylaxis in colorectal surgery. No benefit from high dosage or combination with nalidixic acid.

PA Kling, LG Burman - Acta chirurgica scandinavica, 1988 - europepmc.org
In an open prospective study of postoperative infectious complications, patients undergoing
elective colorectal surgery were randomly allocated to one of three groups receiving …

Twelve-hourly dosage schedule for oral and intravenous metronidazole

P Earl, PR Sisson, HR Ingham - Journal of Antimicrobial …, 1989 - academic.oup.com
Paired samples of blood were examined from 48 patients undergoing major surgery who
were receiving metronidazole at a 12-hourly dosage interval, as part of a regimen for …

Metronidazole need not be combined with an aminoglycoside when used for prophylaxis in elective colorectal surgery

DL Morris, MM Hares, RJ Voogt, DW Burdon… - Journal of Hospital …, 1983 - Elsevier
A prospective randomized controlled study has compared prophylactic intravenous
metronidazole alone with the combination of metronidazole and gentamicin in 100 patients …

A comparison of intravenous and oral metronidazole as prophylactic in colorectal surgery

FD Beggs, RS Jobanputra… - British Journal of …, 1982 - Wiley Online Library
In a prospective randomized double‐blind trial we have compared oral (n= 46) and
parenteral prophylaxis (n= 51) with metronidazole in elective colonic resection. All patients …

Appropriateness of metronidazole use in a teaching hospital

JC Wang, JM Conly, SD Shafran - American Journal of Health …, 1989 - academic.oup.com
The appropriateness of metronidazole use at a teaching hospital was determined by a
retrospective audit. All orders for metronidazole received by the hospital pharmacy from …

Inappropriate use of metronidazole in gastrointestinal surgery

CJH INGOLDBY, PH Dean, P Vowden… - Alimentary …, 1989 - Wiley Online Library
Pharmacokinetic data suggest that current treatment regimens of metronidazole in
abdominal surgery are not always appropriate. We have examined antibiotic concentrations …

Statistical analysis of serum metronidazole levels in patients receiving the drug mainly by suppository

GW Houghton, R Templeton - Journal of Antimicrobial …, 1978 - academic.oup.com
Metronidazole administered by the rectal route has been shown to be clinically effective in
reducing the incidence of post-operative infection in patients undergoing abdominal surgery …