Effects of remote ischemic preconditioning in high-risk patients undergoing cardiac surgery (Remote IMPACT): a randomized controlled trial

M Walsh, R Whitlock, AX Garg, JF Légaré, AE Duncan… - Cmaj, 2016 - Can Med Assoc
Background: Remote ischemic preconditioning is a simple therapy that may reduce cardiac
and kidney injury. We undertook a randomized controlled trial to evaluate the effect of this …

[HTML][HTML] A multicenter trial of remote ischemic preconditioning for heart surgery

P Meybohm, B Bein, O Brosteanu… - … England Journal of …, 2015 - Mass Medical Soc
Background Remote ischemic preconditioning (RIPC) is reported to reduce biomarkers of
ischemic and reperfusion injury in patients undergoing cardiac surgery, but uncertainty …

Effects of delayed remote ischemic preconditioning on peri-operative myocardial injury in patients undergoing cardiac surgery—a randomized controlled trial

TK Kim, JJ Min, YJ Cho, DJ Hausenloy, H Ahn… - International journal of …, 2017 - Elsevier
Background Remote ischemic preconditioning (RIPC) has two time windows for organ
protection: acute and delayed. Previous studies have mainly focused on the acute time …

Long-term clinical outcomes of Remote Ischemic Preconditioning and Postconditioning Outcome (RISPO) trial in patients undergoing cardiac surgery

YJ Cho, EH Lee, K Lee, TK Kim, DM Hong… - International journal of …, 2017 - Elsevier
Background Remote ischemic conditioning has been shown to confer myocardial protection.
However, there is still no sufficient data on its long-term clinical outcomes. We analyzed the …

Effect of remote ischemic preconditioning on kidney injury among high-risk patients undergoing cardiac surgery: a randomized clinical trial

A Zarbock, C Schmidt, H Van Aken, C Wempe… - Jama, 2015 - jamanetwork.com
Importance No interventions have yet been identified to reduce the risk of acute kidney injury
in the setting of cardiac surgery. Objective To determine whether remote ischemic …

Remote ischemic preconditioning in patients undergoing cardiovascular surgery: evidence from a meta-analysis of randomized controlled trials

P Sardar, S Chatterjee, A Kundu, H Samady… - International Journal of …, 2016 - Elsevier
Background Remote ischemic preconditioning (RIPC) has been associated with reduced
risk of myocardial injury in patients undergoing cardiovascular surgery, but uncertainty about …

Clinical outcomes of remote ischemic preconditioning prior to cardiac surgery: a meta‐analysis of randomized controlled trials

B Pierce, I Bole, V Patel, DL Brown - Journal of the American Heart …, 2017 - Am Heart Assoc
Background Multiple randomized controlled trials of remote ischemic preconditioning (RIPC)
prior to cardiac surgery have failed to demonstrate clinical benefit. The aim of this updated …

A pilot study investigating the effects of remote ischemic preconditioning in high-risk cardiac surgery using a randomised controlled double-blind protocol

PJ Young, P Dalley, A Garden, C Horrocks… - Basic research in …, 2012 - Springer
The efficacy of remote ischemic preconditioning (RIPC) in high-risk cardiac surgery is
uncertain. In this study, 96 adults undergoing high-risk cardiac surgery were randomised to …

Effect of remote ischemic preconditioning on outcomes in adult cardiac surgery: a systematic review and meta-analysis of randomized controlled studies

J Xie, X Zhang, J Xu, Z Zhang… - Anesthesia & …, 2018 - journals.lww.com
BACKGROUND: Remote ischemic preconditioning (RIPC) has been demonstrated to
prevent organ dysfunction in cardiac surgery patients. However, recent large, prospective …

Remote ischemic preconditioning in cardiac surgery—ineffective and risky?

M Zaugg, E Lucchinetti - New England Journal of Medicine, 2015 - Mass Medical Soc
Every year millions of patients undergo cardiac surgery, which may be associated with short-
and long-term cardiovascular complications in as many as 20% of patients. Although the …