Background: National guidelines for managing diabetes set standards for care. We sought to
determine whether a 1-year intensive multitherapy program resulted in greater goal …

AIM: To assess the impact of an intensive multitherapy (IMT) on perceived quality of life
(QOL), attitudes, knowledge and diabetes self-management in patients with poorly …

The discovery of insulin at the University of Toronto in 1921 and its first administration on
January 11, 1922, dramatically revolutionized the management and outcome of type 1 …

Background Intensified multifactorial intervention—with tight glucose regulation and the use
of renin–angiotensin system blockers, aspirin, and lipid-lowering agents—has been shown …

Objectives: To evaluate the outcome of an early short-term intensive diabetic care program
followed by a regular out-patient shared-care education program. Methods: We …

BACKGROUND: Intensive treatment (IT) of cardiovascular risk factors can halve mortality
among people with established type 2 diabetes but the effects of treatment earlier in the …

Background: There is compelling evidence showing that achieving good glycaemic control
reduces the risk of microvascular complications in people with type 1 and type 2 diabetes …

OBJECTIVE The principal aim is to estimate the benefits of earlier versus later
implementation of intensive therapy in type 1 diabetes with respect to the long-term risks of …

OBJECTIVE—Diabetes treatment and teaching programs (DTTPs) for type 1 diabetes, which
teach flexible intensive insulin therapy to enable dietary freedom, have proven to be safe …

OBJECTIVE To evaluate the effect of intensive diabetes treatment on patient quality of life
assessed by the Diabetes Quality-of-Life Measure, the Symptom Checklist-90R, the Medical …