• Intravenous methylprednisolone has been used as a neuroprotective strategy based on
limited evidence, but this is not a standard of care and may be associated with an increased …

Acute spinal cord injury (SCI) is a devastating neurological disorder that can affect any
individual at a given instance. Current treatment options for SCI include the use of high dose …

There are no drugs specifically approved for spinal cord injury that directly address the
underlying damage to neural tissue. Immediate treatment with methylprednisolone sodium …

Over the past 2 decades, advances in understanding the pathophysiology of spinal cord
injury (SCI) have stimulated the recent emergence of several therapeutic strategies that are …

Objective: To review the major pharmacological trials in acute spinal cord injury (SCI) that
have been conducted over the past 25 years. Methods: Review article. Results: The …

An increasing number of therapies for spinal cord injury (SCI) are emerging from the
laboratory and seeking translation into human clinical trials. Many of these are administered …

Spinal cord injury (SCI) remains a common and devastating problem of modern society.
Through an understanding of underlying pathophysiologic mechanisms involved in the …

OBJECTIVE: To provide a comprehensive review of the treatment trials in the field of spinal
cord injury, emphasizing what has been learned about the effectiveness of the agents and …

The history of spinal cord injuries starts with the ancient Egyptian medical papyrus known as
the Edwin Smith Surgical Papyrus. The papyrus written about 2500 BC by the physician and …

Cell transplantation therapies have become a major focus in pre-clinical research as a
promising strategy for the treatment of spinal cord injury (SCI). In this article, we …