Background: Recent reports suggest that Clostridium difficile colitis may be evolving into a
more severe disease. During the second half of 2002 we noted an increase in the number of …

Background. Recent outbreaks of severe cases of Clostridium difficile-associated diarrhea
(CDAD) reported in North America, the United Kingdom, and The Netherlands have …

Background Clinicians who treat patients with Clostridium difficile–associated diarrhea
(CDAD) in Quebec, Canada, have noted an apparent increase in the proportion of patients …

Clostridium difficile-associated diarrhea (CDAD) is regarded as an emerging nosocomial
infection. All patients positive for C. difficile in Sweden were recorded during 1995, including …

Objective: Clostridium difficile gastrointestinal disease is an important nosocomial infection
and is associated with recent antibiotic use. This study evaluated C. difficile-associated …

■ ABSTRACT Clostridium difficile-associated disease (CDAD) can range from
uncomplicated diarrhea to sepsis and even death. CDAD rates and severity are increasing …

Background. Clostridium difficile causes diarrhea that ranges from a benign, self-limiting
antibiotic use–associated disease to a life-threatening pseudomembranous colitis …

Background. During an epidemic of Clostridium difficile-associated disease (CDAD) caused
by a strain that is a hyper-producer of toxins A and B, the frequency of a first recurrence after …

Background. The incidence and severity of Clostridium difficile–associated diarrhea (CDAD)
has been increasing, and there have been recent reports of metronidazole treatment failure …

Objectives: Clostridium difficile associated diarrhoea (CDAD) is a hospital acquired infection
in which optimal methods for diagnosis and the scale of the problem in the community …