Background: Although fluoroquinolones are sometimes associated with mild, transient
elevations in aminotransferase levels, serious acute liver injury is uncommon. Regulatory …

Study Objective To estimate the incidence and relative risk of a hospitalization or emergency
visit for noninfectious liver injury in users of eight oral antimicrobials—amoxicillin, amoxicillin …

Purpose Fluoroquinolones are popular and widely used in primary care and hospital
settings. Premarketing studies showed a favourable side-effect profile. However, significant …

Purpose Results of a pharmacoepidemiologic evaluation of fluoroquinolone-associated
hepatotoxicity using national hospital admissions data on Veterans Affairs (VA) patients are …

BACKGROUND & AIMS: Fluoroquinolone-induced liver injury is rare; no prospective studies
of well-characterized case series have been published. We studied patients with …

1. Kane SV, Cohen RD, Aikens JE, Hanauer SB. Predictors of non-compliance with
mesalamine in quiesecent ulcerative colitis. Am J Gastroenterol 2001; 96: 2929–32. 2 …

Objective: Challenging differential diagnosis Background: Ciprofloxacin is a commonly used
fluoroquinolone antibiotic. It is occasionally associated with benign elevations in liver …

Moxifloxacin is a newer-generation synthetic fluoroquinolone that is used for treatment of
acute bacterial sinusitis, acute exacerbation of chronic bronchitis, community acquired …

Ciprofloxacin is a fluorinated quinolone antibiotic with relatively low occurrence of adverse
side effects. However, increasing evidence suggests that ciprofloxacin may cause severe …

Objective: Challenging differential diagnosis Background: Drug-induced liver injury (DILI)
can present clinically as a spectrum that includes asymptomatic elevation of transaminases …