[HTML][HTML] Ribavirin in the treatment of SARS: A new trick for an old drug?

G Koren, S King, S Knowles, E Phillips - Cmaj, 2003 - Can Med Assoc
* The treatment dose of ribavirin has been reduced significantly from earlier
recommendations because of a lack of information to support the in vitro efficacy of ribavirin …

Adverse effects of ribavirin and outcome in severe acute respiratory syndrome: experience in two medical centers

HE Chiou, CL Liu, MJ Buttrey, HP Kuo, HW Liu, HT Kuo… - Chest, 2005 - Elsevier
Study objectives To assess the effect of ribavirin-induced anemia on the outcome of severe
acute respiratory syndrome (SARS). Design A retrospective observational study. Setting Two …

Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings

CM Chu, VCC Cheng, IFN Hung, MML Wong, KH Chan… - Thorax, 2004 - thorax.bmj.com
Background: The clinical response of patients with severe acute respiratory syndrome
(SARS) to a combination of lopinavir/ritonavir and ribavirin was examined after establishing …

[PDF][PDF] Pharmacologic treatment of SARS: current knowledge and recommendations

DYH Tai - Annals-Academy of Medicine Singapore, 2007 - annals.edu.sg
The severe acute respiratory syndrome (SARS) pandemic caught the world by surprise in
2003 and spread rapidly within a relatively short period of time. Hence, randomised …

[HTML][HTML] SARS: systematic review of treatment effects

LJ Stockman, R Bellamy, P Garner - PLoS medicine, 2006 - journals.plos.org
Background The SARS outbreak of 2002–2003 presented clinicians with a new, life-
threatening disease for which they had no experience in treating and no research on the …

Investigational use of ribavirin in the treatment of severe acute respiratory syndrome, Singapore, 2003

HN Leong, B Ang, A Earnest, C Teoh… - Tropical Medicine & …, 2004 - Wiley Online Library
Objective Ribavirin is a broad spectrum nucleoside analogue efficacious in the treatment of
several viral infections. In the recent severe acute respiratory syndrome (SARS) outbreak …

Novel coronavirus and severe acute respiratory syndrome

AR Falsey, EE Walsh - The Lancet, 2003 - thelancet.com
Peiris and colleagues suggest that early therapy with intravenous ribavirin and high-dose
glucocorticosteroids may be beneficial. However, the lack of untreated control patients …

Adverse events associated with high‐dose ribavirin: evidence from the Toronto outbreak of severe acute respiratory syndrome

MP Muller, L Dresser, J Raboud… - … : The Journal of …, 2007 - Wiley Online Library
Study Objectives. To distinguish adverse events related to ribavirin therapy from those
attributable to severe acute respiratory syndrome (SARS), and to determine the rate of …

Common adverse events associated with the use of ribavirin for severe acute respiratory syndrome in Canada

SR Knowles, EJ Phillips, L Dresser… - Clinical infectious …, 2003 - academic.oup.com
Although information on efficacy and adverse drug reactions is lacking, ribavirin has been
used empirically for the treatment of severe acute respiratory syndrome (SARS). We report …

Current concepts in SARS treatment

T Fujii, T Nakamura, A Iwamoto - Journal of infection and chemotherapy, 2004 - Springer
The outbreak of severe acute respiratory syndrome (SARS) has drawn enormous attention
and caused fear worldwide since early 2003. The disease appears to be under control now; …