Heterozygous familial hypercholesterolemia (HeFH) is a monogenic disorder that affects
about 1 in 500 people, with a higher prevalence in certain subpopulations such as people of …

Abstract Aims Homozygous familial hypercholesterolaemia (HoFH) is a rare disorder usually
caused by mutations in both alleles of the low-density lipoprotein receptor gene (LDLR) …

Background Some recently emerged lipid-lowering therapies are currently restricted to
patients with homozygous familial hypercholesterolemia (HoFH), and studies are underway …

Abstract Aims Homozygous familial hypercholesterolaemia (HoFH) is a rare life-threatening
condition characterized by markedly elevated circulating levels of low-density lipoprotein …

Abstract Purpose of Review Heterozygous familial hypercholesterolemia (HeFH) is the most
common monogenic autosomal dominant disorder. However, the condition is often …

Familial hypercholesterolemia (FH) is an inherited disorder with retarded clearance of
plasma LDL caused by mutations of the genes involved in the LDL receptor-mediated …

Homozygous familial hypercholesterolemia (HoFH) is a rare, genetic disorder characterized
by an absence or impairment of low-density lipoprotein receptor (LDLR) function resulting in …

Familial hypercholesterolemia (FH) is an inherited disease characterized by the deposition
of LDL in tissues causing premature atherosclerosis. Many genes are implicated in FH …

Familial hypercholesterolaemia (FH) is an autosomal co-dominantly inherited condition
resulting from mutations of the low-density lipoprotein (LDL) receptor which occur in …

Aims Homozygous autosomal dominant hypercholesterolaemia (hoADH), an orphan
disease caused by mutations in low-density lipoprotein receptor (LDLR), apolipoprotein B …