Background Studies of cardiac resynchronization therapy in addition to an implantable
cardioverter defibrillator in patients with mild to moderate congestive heart failure had not …

Context Progressive heart failure is the most common mechanism of death among patients
with advanced heart failure. Cardiac resynchronization, a pacemaker-based therapy for …

Aims Cardiac resynchronization therapy (CRT) with or without a defibrillator reduces
morbidity and mortality in selected patients with heart failure (HF) but response can be …

Numerous clinical trials have evaluated the safety and efficacy of cardiac resynchronization
therapy in patients with moderate or severe heart failure and ventricular dyssynchrony. Initial …

Abstract Background The Resynchronization–Defibrillation for Ambulatory Heart Failure
Trial (RAFT) showed a greater benefit with respect to mortality at 5 years among patients …

Up to 50% of patients with chronic systolic heart failure have interventricular conduction
delays, such as left bundle branch block, that result in abnormal electrical depolarization of …

Abstract Aims The CArdiac REsynchronization-Heart Failure study randomized patients with
left ventricular ejection fraction≤ 35%, markers of cardiac dyssynchrony, and persistent …

Objective To review the evidence base from randomised controlled trials of combined
cardiac resynchronisation therapy and implantable cardioverter defibrillator therapy in left …

The device era in heart failure has been heralded by successes in the realm of pacemakers,
implantable defibrillators, and ventricular assist devices. In particular, the concept of cardiac …

Many diagnostic and therapeutic advances have been reached for congestive heart failure
(HF). However, despite clinical improvement and longer survival conferred by new …