Exacerbations of chronic obstructive pul monary disease (COPD) are character ized by
worsening respiratory symp toms, which are almost always accompanied by an increase in …

Chronic obstructive pulmonary disease (COPD) exacerbations are associated with
significant morbidity and mortality (1). Among the major goals of COPD treatment is the …

Prevention of COPD exacerbations is paramount given the adverse consequences on
quality of life, lung function, and survival. Macrolide therapy for 1 year, in addition to usual …

Introduction Macrolides are of unique interest in preventing COPD exacerbations because
they possess a variety of antibacterial, antiviral and anti-inflammatory properties. Recent …

Background: Macrolide antibiotics have anti-inflammatory effects, and long-term
administration may reduce chronic obstructive pulmonary disease (COPD) exacerbations …

Background Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) can
lead to high frequencies and rates of hospitalization and mortality. Macrolides are a class of …

Background: Chronic obstructive pulmonary disease (COPD) is currently the fourth largest
fatal disease in the world, and is expected to rise to third place by 2020. Frequent acute …

Acute exacerbations are a major contributor to health care costs and a leading cause of
death in patients with chronic obstructive pulmonary disease (COPD). A reduction in acute …

The number of senile patients with chronic obstructive pulmonary disease (COPD) has
recently increased due to an increase in life expectancy, the habit of smoking and the …

Chronic inflammation plays a central role in the pathogenesis of chronic obstructive
pulmonary disease (COPD). However, there are no effective anti-inflammatory …