Osteogenesis imperfecta is a heterogeneous group of inherited disorders characterized by
bone fragility and recurrent fractures. It is currently classified into four types on clinical …

Osteogenesis imperfecta is the name given to a group of disorders caused by defective
collagen in various tissues. The most important clinical feature is an increased liability to …

Osteogenesis imperfecta (OI) is an inherited disorder in which affected individuals are
stigmatized by virtue of physical differences from their peers. The extent to which these …

Genetic counseling in osteogenesis imperfecta (01) is designed to give families an accurate
estimate of the recurrence risk and an understanding of the burden and clinical variability in …

Osteogenesis imperfecta describes a group of heritable disorders characterized by
excessive bony fragility and reduced skeletal mass. It is classified in terms of its clinical …

Within the past decade osteogenesis imperfecta has come of age. 2 No longer a mere
orthopaediccuriosity, its problems attract paediatricians, metabolic physicians, and ortho …

Increased bone fragility, a facultative tendency of skeletal deformations and radiological
signs of osteopenia are characteristic symptoms of the clinically heterogenous disorder of …

The major clinical feature that defines osteogenesis imperfecta (OI) is bone fragility. We
begin the chapter with a discussion of the history, prevalence, and classification of OI. After a …

An epidemiological and genetical study of osteogenesis imperfecta (OI) in Victoria, Australia
confirmed that there are at least four distinct syndromes at present called OI. The largest …

Osteogenesis imperfecta is a heterogenous group of inherited conditions arising from a
variety of biochemical and morphological collagen defects. The broad manifestations of …