Statins and postoperative delirium

ER Marcantonio - CMAJ, 2008 - Can Med Assoc
Delirium (acute confusional state) may be the most common postoperative complication in
elderly people. It is associated with substantial morbidity, mortality and cost. 1 Two decades …

Delirium after elective surgery among elderly patients taking statins

DA Redelmeier, D Thiruchelvam, N Daneman - Cmaj, 2008 - Can Med Assoc
Background: Postoperative delirium after elective surgery is frequent and potentially serious.
We sought to determine whether the use of statin medications was associated with a higher …

Preoperative use of statins is associated with reduced early delirium rates after cardiac surgery

R Katznelson, GN Djaiani, MA Borger… - The Journal of the …, 2009 - pubs.asahq.org
Background Delirium is an acute deterioration of brain function characterized by fluctuating
consciousness and an inability to maintain attention. Use of statins has been shown to …

Preoperative statin therapy is not associated with a decrease in the incidence of delirium after cardiac operations

G Mariscalco, M Cottini, M Zanobini, S Salis… - The Annals of thoracic …, 2012 - Elsevier
BACKGROUND: Delirium after cardiac operations is associated with significant morbidity
and death. Statins have been recently suggested to exert protective cerebral effects. This …

[HTML][HTML] Effects of perioperative rosuvastatin on postoperative delirium in elderly patients: A randomized, double-blind, and placebo-controlled trial

XQ Xu, JZ Luo, XY Li, HQ Tang… - World journal of clinical …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Experimental evidence has indicated the benefits of statins for the treatment
of postoperative delirium. Previously, clinical trials did not reach definite conclusions on the …

Preoperative statins are associated with a reduced risk of postoperative delirium following vascular surgery

DS Lee, MY Lee, CM Park, DI Kim, YW Kim, YJ Park - PLoS One, 2018 - journals.plos.org
Delirium is a common complication of vascular surgery. The protective effect of preoperative
statins on delirium after vascular surgery is controversial. The authors hypothesized that …

Statins might contribute to postoperative delirium

JC Drummond, BP Head, PM Patel - The Journal of the American …, 2010 - pubs.asahq.org
In the timely and welcome discussion by Mantz et al. 1 of postoperative delirium in an
octogenarian, the patient's preoperative use of a statin is mentioned but is not considered in …

Review of postoperative delirium in geriatric patients undergoing hip surgery

P Rizk, W Morris, P Oladeji… - … orthopaedic surgery & …, 2016 - journals.sagepub.com
Postoperative delirium is a serious complication following hip surgery in elderly patients that
can adversely affect outcomes in both hip fracture and arthroplasty surgery. Recently, the …

Postoperative delirium after hip fracture

BD Robertson, TJ Robertson - JBJS, 2006 - journals.lww.com
A hip fracture is sustained by 250,000 Americans every year1, and that number is expected
to double by 20402. The most frequent complication associated with hip fracture in elderly …

[PDF][PDF] Management of common postoperative complications: delirium

H Javedan, S Tulebaev - Clinics in geriatric medicine, 2014 - researchgate.net
Delirium is a common postoperative complication that increases both mortality and morbidity
in elderly patients. 1, 2 Delirium on its own has been associated with higher in-hospital …