Alcoholic versus aqueous chlorhexidine for skin antisepsis: the AVALANCHE trial

D Charles, CF Heal, M Delpachitra, M Wohlfahrt… - Cmaj, 2017 - Can Med Assoc
BACKGROUND: Preoperative skin antisepsis is routine practice. We compared alcoholic
chlorhexidine with aqueous chlorhexidine for skin antisepsis to prevent surgical site …

Skin antisepsis with chlorhexidine versus iodine for the prevention of surgical site infection: a systematic review and meta-analysis

GP Privitera, AL Costa, S Brusaferro, P Chirletti… - American journal of …, 2017 - Elsevier
Background Surgical site infection (SSI) is one of the most frequent health care–associated
infections. One of the practices to reduce their incidence is preoperative skin antisepsis. Two …

Systematic review and cost analysis comparing use of chlorhexidine with use of iodine for preoperative skin antisepsis to prevent surgical site infection

I Lee, RK Agarwal, BY Lee, NO Fishman… - Infection Control & …, 2010 - cambridge.org
Objective. To compare use of chlorhexidine with use of iodine for preoperative skin
antisepsis with respect to effectiveness in preventing surgical site infections (SSIs) and cost …

[HTML][HTML] The forgotten role of alcohol: a systematic review and meta-analysis of the clinical efficacy and perceived role of chlorhexidine in skin antisepsis

M Maiwald, ESY Chan - 2012 - journals.plos.org
Background Skin antisepsis is a simple and effective measure to prevent infections. The
efficacy of chlorhexidine is actively discussed in the literature on skin antisepsis. However …

Chlorhexidine-alcohol versus povidone-iodine as preoperative skin preparation to prevent surgical site infection: a meta-analysis

T Anggrahita, A Wardhana, G Sudjatmiko - Medical Journal of Indonesia, 2017 - mji.ui.ac.id
Background: Surgical site infection remains substantial problems to surgeons and patients
as it increases the morbidity, mortality, length of stay, hospital cost, rate of re-admission, and …

Antiseptic skin agents to prevent surgical site infection after incisional surgery: a randomized, three-armed combined non-inferiority and superiority clinical trial …

SR Smith, J Gani, R Carroll, N Lott, J Hampton… - 2022 - journals.lww.com
Objective: To compare SSI rates between the skin preparation agents: PI-Aq, povidone-
iodine with alcohol (PI-Alc), and chlorhexidine with alcohol (C-Alc). Background: Guidelines …

[HTML][HTML] Chlorhexidine–alcohol versus povidone–iodine for surgical-site antisepsis

RO Darouiche, MJ Wall Jr, KMF Itani… - … England Journal of …, 2010 - Mass Medical Soc
Background Since the patient's skin is a major source of pathogens that cause surgical-site
infection, optimization of preoperative skin antisepsis may decrease postoperative …

Cluster-randomized crossover trial of chlorhexidine–alcohol versus iodine–alcohol for prevention of surgical-site infection (SKINFECT trial)

A Charehbili, MBG Koek, JCA Mol van Otterloo… - BJS open, 2019 - academic.oup.com
Background Surgical-site infection (SSI) is a serious surgical complication that can be
prevented by preoperative skin disinfection. In Western European countries, preoperative …

Comparison of chlorhexidine–isopropanol with isopropanol skin antisepsis for prevention of surgical-site infection after abdominal surgery

JC Harnoss, O Assadian, A Kramer… - Journal of British …, 2018 - academic.oup.com
Background Prevention of surgical-site infection (SSI) has received increasing attention.
Clinical trials have focused on the role of skin antisepsis in preventing SSI. The benefit of …

Pitfalls in evidence assessment: the case of chlorhexidine and alcohol in skin antisepsis

M Maiwald, ESY Chan - Journal of Antimicrobial Chemotherapy, 2014 - academic.oup.com
Chlorhexidine has attracted increasing attention for its role in skin antisepsis in recent years.
It was tested in several prominent clinical trials and subsequently recommended in important …