Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trials
C Barbui, TA Furukawa, A Cipriani - Cmaj, 2008 - Can Med Assoc
Background: Concern has been raised about the efficacy of antidepressant therapy for major
depression in adults. We undertook a systematic review of published and unpublished …
depression in adults. We undertook a systematic review of published and unpublished …
[HTML][HTML] Randomized, placebo-controlled trials of antidepressants for acute major depression: thirty-year meta-analytic review
J Undurraga, RJ Baldessarini - Neuropsychopharmacology, 2012 - nature.com
Antidepressant–placebo response-differences (RDs) in controlled trials have been
declining, potentially confounding comparisons among older and newer drugs. For clinically …
declining, potentially confounding comparisons among older and newer drugs. For clinically …
A meta-analysis of the efficacy and tolerability of paroxetine versus tricyclic antidepressants in the treatment of major depression
SA Montgomery - International clinical psychopharmacology, 2001 - journals.lww.com
This meta-analysis examined efficacy and tolerability data from 39 randomized, double-
blind, parallel-group studies comparing paroxetine (n= 1924) with clomipramine (n= 141) or …
blind, parallel-group studies comparing paroxetine (n= 1924) with clomipramine (n= 141) or …
Paroxetine versus other anti‐depressive agents for depression
Background Paroxetine is the most potent inhibitor of the reuptake of serotonin of all
selective serotonin reuptake inhibitors (SSRIs) and has been studied in many randomised …
selective serotonin reuptake inhibitors (SSRIs) and has been studied in many randomised …
Initial severity of major depression and efficacy of new generation antidepressants: individual participant data meta‐analysis
Objective The role of baseline severity as effect modifier in various psychiatric disorders is a
topic of controversy and of clinical import. This study aims to examine whether baseline …
topic of controversy and of clinical import. This study aims to examine whether baseline …
A comparison of paroxetine and placebo in depressed outpatients
GC Dunbar, JL Claghorn, A Kiev… - Acta psychiatrica …, 1993 - Wiley Online Library
To compare the safety and efficacy of paroxetine (n= 167) and placebo (n= 169), data from 4
centres using the same protocol were pooled. A double‐blind parallel group design was …
centres using the same protocol were pooled. A double‐blind parallel group design was …
Metareview on short-term effectiveness and safety of antidepressants for depression: an evidence-based approach to inform clinical practice
Objectives: To examine the available scientific literature for answers to clinically relevant
questions regarding the effectiveness and tolerability of antidepressant drugs (ADs) for the …
questions regarding the effectiveness and tolerability of antidepressant drugs (ADs) for the …
Does randomized evidence support sertraline as first-line antidepressant for adults with acute major depression? A systematic review and meta-analysis
Objective: Preliminary evidence suggested that sertraline might be slightly superior to other
antidepressant medications in terms of efficacy. The aim of this study was to carry out a …
antidepressant medications in terms of efficacy. The aim of this study was to carry out a …
Paroxetine versus placebo: a double-blind comparison in depressed patients.
JL Claghorn, A Kiev, K Rickels, WT Smith… - The Journal of clinical …, 1992 - europepmc.org
Background Paroxetine is a potent and selective serotonin reuptake inhibitor (SSRI). The
present study assessed the efficacy and tolerability of paroxetine against placebo in …
present study assessed the efficacy and tolerability of paroxetine against placebo in …
General and comparative efficacy and effectiveness of antidepressants in the acute treatment of depressive disorders: a report by the WPA section of …
TC Baghai, P Blier, DS Baldwin, M Bauer… - European archives of …, 2011 - Springer
Current gold standard approaches to the treatment of depression include
pharmacotherapeutic and psychotherapeutic interventions with social support. Due to …
pharmacotherapeutic and psychotherapeutic interventions with social support. Due to …
