Discussion Gross motor delay, weakness and hypotonia are a common clinical presentation
of neuromuscular disorders, such as congenital myopathies and cerebral palsy. Rickets can …

CASE PRESENTATION A 2-year, 10-month-old White girl presented to a pediatric clinic with
an abnormal wide gait and genu varum. She had been an established patient at the clinic …

A case of pseudovitamin D deficiency (Vitamin D dependent rickets type I) is presented, who
initially responded to physiological doses of calcitriol but developed nephrolithiasis and …

Although Vitamin D deficiency is the most common form of rickets worldwide, when there is a
failure to respond to cholecalciferol, inborn errors of vitamin D metabolism should be …

I read with interest the article by Oginni et al. 1 on the etiology of rickets in Nigerian children.
This article touches on an interest that I have had for many years in vitamin D, calcium, and …

A 5-month-old male infant of non-consanguineous parents presented life threatening
laringospastic crises and carpo-pedal spasms since he was 4 months old. Neither symptoms …

We refer to your recent editorial1 and article detailing the reappearance of rickets in your
ethnic group, particularly in the offspring of breast-feeding African American women. 2 We …

Vitamin D-dependent rickets type 1 is an autosomal recessive disorder caused by an
inactivating mutation of the 25-hydroxyvitamin-D-1α-hydroxylase (CYP27B1) gene. Clinical …

A 12-year-old girl from Ukraine was hospitalized for evaluation of a history of long-bone
fractures and failure to thrive. On initial presentation, she had hypocalcemia (calcium level …

Rickets is a disease of growing bones characterized by softening of bones as a result of
defective mineralization of cartilage in the epiphyseal growth plate. The predominant cause …