Ovarian cancer in Canada

B Moloughney, J Snider, L Villeneuve - 2000 - Can Med Assoc
Ovarian cancer is the fifth most diagnosed cancer among Canadian women, accounting for
4% of all new cases. It is also the fifth leading cause of cancer-related death among women …

Hereditary Ovarian Cancer

A George - Advances in Diagnosis and Management of Ovarian …, 2022 - Springer
Ovarian cancer is the fifth most common cause of cancer death in women, with over 300,000
new diagnoses globally each year. The vast majority of patients will present with advanced …

[HTML][HTML] AGO Austria recommendations for genetic testing of patients with ovarian cancer

C Marth, M Hubalek, E Petru, S Polterauer… - Wiener klinische …, 2015 - ncbi.nlm.nih.gov
In Austria, 700 women are diagnosed every year with ovarian carcinoma. Approximately
15% of the patients with epithelial ovarian cancer have a germline mutation in the BRCA1 or …

[HTML][HTML] Hereditary Breast and Ovarian Cancer: Current Concepts of Prevention and Treatment

A Grabenstetter, C Lazaro, G Turashvili - Frontiers in oncology, 2020 - frontiersin.org
Breast cancer is the leading cause of cancer-related death in women worldwide. Whilst
ovarian cancer is less common, it remains challenging due to late detection and high …

Hereditary breast and ovarian cancer syndrome: Considering the complexities

L Senter - Current Problems in Cancer, 2014 - Elsevier
Hereditary breast and ovarian cancer syndrome (HBOC) is a well-described hereditary
cancer predisposition syndrome caused by mutations in BRCA1 and BRCA2. Several …

Discussion: hereditary ovarian cancer

BY Karlan, J Boyd, L Strong, J Garber, J Fountain… - Gynecologic …, 2003 - Elsevier
The majority of ovarian cancers occur sporadically in women without a family history. Only
approximately 10% of ovarian cancers can be attributed to germline mutations in highly …

[HTML][HTML] Hereditary ovarian and breast cancer: what have we learned?

HT Lynch, C Snyder, MJ Casey - Annals of oncology, 2013 - Elsevier
An autosomal-dominant inherited trait predisposing women to both breast cancer (BC) and
ovarian cancer (OC) was first described in 1971. Subsequent strides were made in …

Hereditary ovarian cancers: from BRCA mutations to clinical management. A modern appraisal

A Tinelli, A Malvasi, G Leo, D Vergara, M Pisanò… - Cancer and Metastasis …, 2010 - Springer
In the past few years, ovarian cancer research has focused increasingly on disease
prevention; but an increasing number of women refer to gynecology and clinical genetics …

Clinical aspects of familial ovarian cancer-current status and issues in Japan

M Sekine, K Yoshihara, K Tanaka - Gan to Kagaku ryoho. Cancer & …, 2012 - europepmc.org
Familial ovarian cancer occurs as part of two genetically distinct syndromes: hereditary
breast and ovarian cancer (HBOC) and hereditary nonpolyposis colorectal cancer (HNPCC) …

Ovarian cancer is in many ways a heterogeneous disease

S Malander, E Hjerpe, J Carlson, Å Borg - Lakartidningen, 2015 - europepmc.org
Ovarian cancer develops due to a complex interplay between hereditary and environmental
factors. Although often described as one disease, ovarian cancer is actually a group of …