Background: Clinical trials and meta-analyses have produced conflicting results of the
efficacy of unconjugated pneumococcal polysaccharide vaccine in adults. We sought to …

Background: Because of the prevalence of pneumococcal pneumonia, the substantial
morbidity and mortality associated with many pneumococcal infections, and an increase in …

Ten prospective clinical trials conducted in elderly and high-risk adults have failed to show
that pneumococcal vaccine prevents pneumococcal bacteraemia and all pneumonia …

The use of pneumococcal polysaccharide vaccine has remained controversial since
licensure, especially in the elderly. Observational studies form much of the evidence base …

Pneumococcal polysaccharide vaccine is recommended in western countries for individuals
at high risk of pneumococcal illness. We undertook a systematic review of randomised …

The use of pneumococcal polysaccharide vaccine (PPV) is low in some countries, maybe
because of doubts regarding its efficacy. This meta-analysis aims at combining evidence …

OBJECTIVE: To determine the clinical effectiveness of pneumococcal vaccine. DATA
SOURCES: Computerized searches of MEDLINE, EMBASE, and SCISEARCH databases …

The objective was to review the evidence of effectiveness of the polyvalent polysaccharide
pneumococcal vaccine from prospective properly randomised controlled trials comparing …

Pneumococcal disease constitutes a major global health problem. Adults aged over 50
years and younger adults with specific chronic health conditions are at risk for invasive …

PURPOSE: To study the efficacy of pneumococcal capsular polysaccharide vaccine among
the elderly by use of a population-based intervention in one township, Varkaus, Eastern …