Tranexamic acid for trauma-related hemorrhage
A Ackery, S Rizoli - CMAJ, 2014 - Can Med Assoc
Uncontrolled hemorrhage causes 30%–45% of all trauma-related deaths. The Clinical
Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2) trial, an …
Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2) trial, an …
Tranexamic acid for trauma patients—more lives to save and outcomes to consider
H Shakur-Still, I Roberts - New England Journal of Medicine, 2023 - Mass Medical Soc
Traumatic hemorrhage accounts for approximately 2 million deaths each year worldwide. 1
In 2010, the results of the Clinical Randomisation of an Antifibrinolytic in Significant …
In 2010, the results of the Clinical Randomisation of an Antifibrinolytic in Significant …
Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial
Objectives To examine whether the effect of tranexamic acid on the risk of death and
thrombotic events in patients with traumatic bleeding varies according to baseline risk of …
thrombotic events in patients with traumatic bleeding varies according to baseline risk of …
Tranexamic acid therapy decreases mortality of traumatic hemorrhagic shock
A Muñoz-Sánchez, F Murillo-Cabezas - Medicina Intensiva (English Edition), 2011 - Elsevier
The CRASH 2, a randomized, double-blind, controlled trial that enrolled 20,211 adult trauma
patients, has shown that the administration of tranexamic acid significantly reduces all-cause …
patients, has shown that the administration of tranexamic acid significantly reduces all-cause …
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial
Crash-2 Collaborators - The Lancet, 2011 - Elsevier
BACKGROUND: The aim of the CRASH-2 trial was to assess the effects of early
administration of tranexamic acid on death, vascular occlusive events, and blood transfusion …
administration of tranexamic acid on death, vascular occlusive events, and blood transfusion …
Tranexamic acid treatment for trauma victims
Worldwide, traumatic injury is responsible for over 5 million deaths per year, the majority due
to exsanguination and head injury. The antifibrinolytic drug tranexamic acid is the only drug …
to exsanguination and head injury. The antifibrinolytic drug tranexamic acid is the only drug …
[HTML][HTML] Use of tranexamic acid in major trauma: a sex-disaggregated analysis of the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH …
Background Women are less likely than men to receive some emergency treatments. This
study examines whether the effect of tranexamic acid (TXA) on mortality in trauma patients …
study examines whether the effect of tranexamic acid (TXA) on mortality in trauma patients …
[HTML][HTML] Tranexamic acid–A recipe for saving lives in traumatic bleeding
I Roberts - Alexandria Journal of Medicine, 2012 - Taylor & Francis
Using kitchen scales, carefully weight out 4 kg of rice and pour it into a deep saucepan. Now
put your hands into the rice and let the grains run between your fingers. Contemplate …
put your hands into the rice and let the grains run between your fingers. Contemplate …
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant hemorrhage (CRASH-2): a randomized …
H Shakur, I Roberts - 50 Landmark Papers every Trauma …, 2019 - api.taylorfrancis.com
This important paper addressed a key clinical question, which was exceptionally novel at the
time of investigation. Namely, could the early administration of 1 gram of tranexamic acid …
time of investigation. Namely, could the early administration of 1 gram of tranexamic acid …
Tranexamic acid in trauma: After 3 hours from injury, when is it safe and effective to use again?
Tranexamic acid (TXA) has proven mortality benefit if used early after traumatic injury, likely
related to a combination of bleeding reduction and other non‐bleeding effects. If TXA is …
related to a combination of bleeding reduction and other non‐bleeding effects. If TXA is …
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