An animal model is described in which mild transitory renal impairment is induced with
glycerol and the nephrotoxic effects of cephalosporin antibiotics and furosemide studied …

ABSTRACT Bendirdjian, Jean-Pierre, Donald J. Prime, Marc C. Browning, Chien-Yin Hsu
and Bruce M. Tune: Additive nephrotoxicity of cephalosporins and aminoglycosides in the …

Cephaloridine is known to be nephrotoxic to man and animals. It has recently been
suggested that diuretics may enhance this effect. Experiments in rats were undertaken to …

Reversible acute renal failure from cephalothin (Keflin) 24g daily occurred in a patient with
previously normal renal function." A further patient developed reversible acute renal failure …

To delineate the site and morphology of renal lesions produced by cephalosporin
antibiotics, rabbits and rats were treated with various doses of either cephalothin …

Aminoglycosides were administered subcutaneously twice daily for 10 days to Fischer 344
rats. The rank order of nephrotoxicity of the drugs, as judged by histologic change and the …

OF THE cephalosporin group of antibiotics, cephaloridine has been demonstrated to be a
nephrotoxic agent, and clinical evidence is accumulating to indicate cephalothin sodium as …

Of the various drugs in each of the three major groups of bactericidal antibiotics, the
aminoglycosides regularly carry some risk of producing nephrotoxic side effects [1]. Of the …

A review of synergistic nephrotoxicity associated with the concomitant administration of
aminoglycoside and cephalosporin antibiotics is presented. A combination of these …

Early clinical studies with combined cephaloridine and aminoglycoside therapy suggested
that a synergistic nephrotoxic interaction was possible between agents in these two classes …