The pharmacokinetic behavior of cefazolin and cephalothin was compared in patients with
normal and impaired renal function. With equivalent doses, total levels of cefazolin in serum …

Cephalothin and cephaloridine, semisynthetic congeners of cephalosporin C, are highly
active against nearly all Gram-positive bacteria (except enterococci and methicillin-resistant …

Cefazolin, a new cephalosporin derivative, was studied in the treatment of 105 hospitalized
patients with a variety of infections including endocarditis, pneumonia, and urinary and soft …

Cephaloridine was used to treat 136 bacterial infections in 122 hospitalized patients. Its
antibacterial and clinical effectiveness against serious staphylococcal infections compared …

The cephalosporin antibiotics are semisynthetic antibacterial agents that are closely related,
chemically, to the penicillins. The nucleus of 7-aminocephalosporanic acid is obtained from …

This study was conducted in a" group of district general hospitals" at Chelmsford, Essex. 160
patients received 176 courses of treatment, of which 142 were suitable for analysis. The …

Serious infections caused by gram-negative bacilli continue to wax in frequency of
occurrence. 23, 24, 44, 56, 67, 82, 88 This trend is attributable, in large part, to the spate of …

Table 1. Mean serum levels in the groups with normal kidney and slightly impaired function
after a sigle 500mg intravenous dose Page 1 302 CHEMOTHERAPY MAY 1970 腎 機 能 不 全 …

抄録 The kinetics of broad-spectirum penieillis and cephalosporins were studied in patients
treated with peritoneal and haemodialysis after intravenous, oral or peritoneal load to …

Acute staphylococcal endocarditis, caused as a rule by pyogenic staphylococci, is
indubitably one of the severest bacterial infections in spite of the great progress of …